L0780
Latex beads, amine-modified polystyrene, fluorescent blue
aqueous suspension, 0.05 μm mean particle size
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About This Item
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form
aqueous suspension
composition
Solids, 2.5%
technique(s)
cell based assay: suitable
mean particle size
0.05 μm
fluorescence
λex ~360 nm; λem ~420 nm
application(s)
cell analysis
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Application
Latex beads, amine-modified polystyrene, fluorescent blue has been used:
- to study its effects on the concentration-response relationship of bacterial cell viability
- in the preparation of nanoparticles
- as a model nanoparticle to study interactions with human blood and platelets
Biochem/physiol Actions
Polystyrene latex beads can be used to create latex agglutination systems. Polystyrene latex beads have been used to study the transmission of Mycobacterium leprae, the causative pathogen of leprosy, as well as to develop a method for mass screening for both pulmonary and extrapulmonary tuberculosis.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Catherine McGuinnes et al.
Toxicological sciences : an official journal of the Society of Toxicology, 119(2), 359-368 (2010-12-03)
There is evidence that nanoparticles (NP) can enter the bloodstream following deposition in the lungs, where they may interact with platelets. Polystyrene latex nanoparticles (PLNP) of the same size but with different surface charge-unmodified (umPLNP), aminated (aPLNP), and carboxylated (cPLNP)-were
INDUCTION OF EPIGENETIC RESPONSE TO AMINO-MODIFIED POLYSTYRENE NANOPARTICLES IN HUMAN CELLS
Koprinarova M, et al.
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Optical signatures of small nanoparticles in a conventional microscope.
Eann A Patterson et al.
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J-M Gineste et al.
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The forward scattering of light in a conventional inverted optical microscope by nanoparticles ranging in diameter from 10 to 50nm has been used to automatically and quantitatively identify and track their location in three-dimensions with a temporal resolution of 200ms.
Johanna J Salomon et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 77(3), 392-397 (2010-11-26)
P-glycoprotein/MDR1 (P-gp) is a well-characterised membrane transporter relevant in drug disposition and multi-drug resistance. In this study, we aimed to investigate how far nanoparticulates impair the function of the P-gp transport system and which particle properties govern these interactions. Expression
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