This product is not pharma grade as it is of MQ Level 100 in the MClarity Program.
96329
Kollicoat® SR 30 D
28.5-31.5% solids basis
Synonym(s):
Poly(vinyl acetate) dispersion 30 %, Poly(vinyl acetate) stabilized with polyvinylpyrrolidone and sodium lauryl sulfate
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About This Item
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Quality Level
Assay
25.0-30.0% (saponification value * 0.1534)
28.5-31.5% solids basis
form
dispersion
impurities
≤0.5% sulfated ash (verified on random samples only)
≤0.500% particulate matter, agglomerates
≤100 ppm residual monomer vinyl acetate
≤15000 ppm acetic acid
≤20 ppm heavy metals (verified on random samples only)
≤4.0% povidone (N content/0.126)
pH
3.0-5.5
viscosity
≤100 mPa.s(20 °C, Brookfield RVT) (SP. 1, 100 PRM)
density
1.045-1.065
SMILES string
O(C(=O)C)C=C
InChI
1S/C4H6O2/c1-3-6-4(2)5/h3H,1H2,2H3
InChI key
XTXRWKRVRITETP-UHFFFAOYSA-N
Application
Kollicoat SR is use as a controlled-release coating or as a matrix. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
Analysis Note
appearance and solubility of a film must conform
Legal Information
Kollicoat is a registered trademark of BASF SE
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Sustained-release of buspirone HCl (BUH) was attempted by spray drying after dissolving in two commercially available aqueous polymeric dispersions (Eudragit RS 30 D or Kollicoat SR 30 D) at five different drug:polymer ratios (1:1, 1:2, 1:3, 1:6 and 1:9). The
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 708-717 (2008-02-06)
The purpose of this study was to investigate the mechanism of floating and drug release behaviour of poly(vinyl acetate)-based floating tablets with membrane controlled drug delivery. Propranolol HCl containing tablets with Kollidon SR as an excipient for direct compression and
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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 60(1), 153-158 (2005-04-26)
The purpose of this study was to work out a method of compression of floating pellets with verapamil hydrochloride (VH) in a dose of 40 mg. It was assumed that this form should reside in the stomach floating for several
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During the last decade the number of investigations on the preparation and application of more effective drug release systems on the basis of nanocarriers from biocompatible and biodegradable polymers are considerably increasing. This is notably in force for practically water
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Journal of pharmaceutical sciences, 101(1), 342-353 (2011-09-22)
Amorphous solid dispersions (ASDs) may entail tailor-made dosage form design to exploit their solubility advantage. Surface phenomena dominated the performance of amorphous celecoxib solid dispersion (ACSD) comprising of amorphous celecoxib (A-CLB), polyvinylpyrrolidone, and meglumine (7:2:1, w/w). ACSD cohesive interfacial interactions
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Hi, I would like to ask if Kollicoat® SR 30 D is a pharma grade, so we can use it for R&D activities for pharmaceutical development.
1 answer-
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