93440
Trizma® base
≥99.5%, solid, certified reference material, certified by BAM
Synonym(s):
2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Linear Formula:
NH2C(CH2OH)3
CAS Number:
Molecular Weight:
121.14
Beilstein:
741883
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
product name
Trizma® base, reference material for titrimetry, certified by BAM, >99.5%
grade
reference material
Quality Level
description
aminopeptidase substrate
Assay
>99.5%
quality
certified by BAM
technique(s)
titration: suitable
pH
10.5-12
useful pH range
7-9
pKa (25 °C)
8.1
bp
219-220 °C/10 mmHg (lit.)
mp
167-172 °C (lit.)
solubility
water: soluble (678 g/l at 20 °C)
format
neat
SMILES string
NC(CO)(CO)CO
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key
LENZDBCJOHFCAS-UHFFFAOYSA-N
Looking for similar products? Visit Product Comparison Guide
General description
Trizma® base is a volumetric standard produced under rigorous conditions and measured with the highest possible precision. Its content is determined by volumetric neutralization titration using a combined pH glass electrode. The certified value and uncertainty measurement of the standard are in accordance with ISO Guide 35.
Application
It finds its use as a reference material for the standardization of volumetric solutions in acidimetric titrations.
Features and Benefits
- Available as a solid in a secure glass bottle to ensure its stability for the entire shelf life until opened.
- High-purity material traceable to NIST SRM
- High-quality offering accurate titer determinations
- Accompanied by a certificate of analysis (CoA)
Analysis Note
Exact concentration, expiry date, traceability and detailed information on certification can be found on the certificate and certification report, included in each package. Content and expiry date on label.
Other Notes
The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.
Legal Information
Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Customers Also Viewed
A modified protocol for rapid DNA isolation from plant tissues using cetyltrimethylammonium bromide
Allen CG, et al.
Nature Protocols, 1, 2320-2325 (2006)
Corey A Baron et al.
Magnetic resonance in medicine, 73(3), 1075-1084 (2014-04-12)
An acquisition method that does not increase scan time or specific absorption rate is investigated for reducing the deleterious effects of cerebrospinal fluid (CSF) partial volume effects on diffusion tensor imaging (DTI) tractography. It is based on using a shorter
Filippo Bertoli et al.
Small (Weinheim an der Bergstrasse, Germany), 10(16), 3307-3315 (2014-04-17)
Nanoparticles in contact with cells and living organisms generate quite novel interactions at the interface between the nanoparticle surface and the surrounding biological environment. However, a detailed time resolved molecular level description of the evolving interactions as nanoparticles are internalized
D R Brocks et al.
Clinical pharmacokinetics, 23(6), 415-427 (1992-12-01)
Ketorolac is a new chiral nonsteroidal anti-inflammatory drug (NSAID) which is marketed for analgesia as the racemate. The drug is administered as the water soluble tromethamine salt and is available in tablets or as an intramuscular injection. The absorption of
Vadapalli Chandrasekhar et al.
Inorganic chemistry, 51(16), 8664-8666 (2012-08-08)
A new water-soluble, multisite-coordinating ligand LH(7) was prepared by the condensation of tris(hydroxymethyl)aminomethane with 2,6-diformyl-p-cresol. LH(7) is a selective chemosensor for Cu(2+), under physiological conditions, with visual detection limits of 20 ppm (ambient light conditions) and 4 ppm (UV light
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service