Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 26(3), 215-225 (1988-03-01)
N-Nitroso compounds may well rank high among the genotoxic carcinogens present in our environment. Small amounts of such compounds may be formed in the human stomach after consumption of high-nitrate vegetables. Volatile nitrosamines can be conveniently determined but reliable methods
Drug metabolism and disposition: the biological fate of chemicals, 18(4), 447-452 (1990-07-01)
The single-dose toxicokinetics of monomethylamine has been characterized in the rat by HPLC assay of serial blood samples. Biphasic first-order elimination was observed following an iv bolus dose of 19 mumol/kg with a terminal half-life of 19.1 +/- 1.3 min
The thick ascending limb of Henle's loop (TALH) is thought to be involved in the regulation of the renal urea gradient. We have characterized the uptake of urea (oil density centrifugation and 2-compartment-culture) and volume regulation (impedance measurement) in highly
The in vivo nitrosation capacity of third-instar larvae of Drosophila melanogaster was assessed using the wing somatic mutation and recombination test (SMART). Larvate derived from two different crosses, the standard cross (ST) and the high bioactivation cross (HB) both involving
American journal of physiology. Regulatory, integrative and comparative physiology, 297(2), R313-R322 (2009-05-22)
Gulf toadfish (Opsanus beta) use a unique pulsatile urea excretion mechanism that allows urea to be voided in large pulses via the periodic insertion or activation of a branchial urea transporter. The precise cellular and subcellular location of the facilitated
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