924121
Conjugated Polymer Nanoparticles incorporating iron oxide
fluorescence λem 510B nm, 100 μg/mL in H2O
Synonym(s):
Conjugated polymer nanoparticles, Fluorescent magnetic nanoparticles, Fluorescent nanoparticles, Magneto-conjugated polymer nanoparticles
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About This Item
UNSPSC Code:
12352303
NACRES:
NA.23
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Application
Iron oxide containing conjugated polymer nanoparticles are water-soluble nanoparticles compromising of light-emitting polymer and iron oxide. The presence of iron oxide in core makes these fluorescent nanoparticles distinctly different than conventional dyes as it allows their manipulation with a magnetic field. These nanoparticles possess a ′core-shell′ structure where light-emitting polymer and iron oxide are encapsulated in biocompatible surfactant.
The ′core-shell′ structure consisting of polymer and iron oxide in the core and the biocompatible surfactant in the surrounding shell allows easy covalently bonding of these nanoparticles with biomolecules such streptavidin, antibodies, proteins, nucleic acids, etc and make them suitable for the following applications:
The ′core-shell′ structure consisting of polymer and iron oxide in the core and the biocompatible surfactant in the surrounding shell allows easy covalently bonding of these nanoparticles with biomolecules such streptavidin, antibodies, proteins, nucleic acids, etc and make them suitable for the following applications:
- Fluorescence Microscopy (high content screening, live cell tracking and 3-D cell imaging)
- Immunohistochemistry and Immunocytochemistry
- Flow Cytometry
- Rapid Diagnostic Tests (RDTs)
- Tissue Imaging
- 2-Photon Imaging
- NIR Imaging
Storage and Stability
The robustness of CPNs enables them to be used under high intensity illumination and in extreme experimental conditions if required, while their 24-month shelf-life permits convenient storage at ambient temperatures.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
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General synthesis of high-performing magneto-conjugated polymer core?shell nanoparticles for multifunctional theranostics.
Yan H, et al.
Nano Research, 10, 704-717 (2017)
General synthesis of high-performing magneto-conjugated polymer core?shell nanoparticles for multifunctional theranostics.
Yan H, et al.
Nano Research, 10, 704-704 (2017)
Philip Howes et al.
Journal of the American Chemical Society, 132(28), 9833-9842 (2010-06-25)
Hybrid nanoparticles which incorporate multiple functionalities, such as fluorescence and magnetism, can exhibit enhanced efficiency and versatility by performing several tasks in parallel. In this study, magnetic-fluorescent semiconductor polymer nanospheres (MF-SPNs) have been synthesized by encapsulation of hydrophobic conjugated polymers
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