36295
2,3-Dichloro-1-propanol
≥97.0% (GC)
Synonym(s):
Glycerol-α,β-dichlorohydrin
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About This Item
Linear Formula:
ClCH2CHClCH2OH
CAS Number:
Molecular Weight:
128.99
Beilstein:
1732060
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Quality Level
Assay
≥97.0% (GC)
density
1.360 g/mL at 20 °C (lit.)
functional group
chloro
hydroxyl
SMILES string
OCC(Cl)CCl
InChI
1S/C3H6Cl2O/c4-1-3(5)2-6/h3,6H,1-2H2
InChI key
ZXCYIJGIGSDJQQ-UHFFFAOYSA-N
General description
2,3-Dichloro-1-propanol belongs to the group of chloropropanols. Inhibitory effects of 2,3-dichloro-1-propanol on T cell both in vivo and in vitro is reported. Improved enantioselective resolution of (R,S)-2,3-dichloro-1-propanol to (S)-2, 3-dichloro-1-propanol by whole cells of a recombinant Escherichia coli in n-heptane-aqueous biphasic system is reported.
Application
2,3-Dichloro-1-propanol may be employed as carbon and energy supplement for the growth of Pseudomonas putida strain (MC4).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Irrit. 2
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
199.4 °F
Flash Point(C)
93 °C
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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We investigated the toxicity of dichloropropanols (DCPs) in hematological findings and serum chemistry. The solutions of two isomers of DCPs, 1,3-dichloro-2-propanol (DC2P) and 2,3-dichloro-1-propanol (DC1P) were dissolved in saline at the concentration of 100 mg/ml, and 0.1 ml of each
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Journal of biotechnology, 188, 42-47 (2014-08-26)
The enantioselective resolution of (R,S)-2,3-dichloro-1-propanol ((R,S)-DCP) to (S)-DCP by whole cells of a recombinant Escherichia coli expressing halohydrin dehalogenase (HHDH) activity was limited by product inhibition. To solve this problem to improve the productivity of (S)-DCP, an n-heptane-aqueous biphasic system
A J Effendi et al.
Applied and environmental microbiology, 66(7), 2882-2887 (2000-07-06)
2,3-Dichloro-1-propanol is more chemically stable than its isomer, 1, 3-dichloro-2-propanol, and is therefore more difficult to degrade. The isolation of bacteria capable of complete mineralization of 2, 3-dichloro-1-propanol was successful only from enrichments at high pH. The bacteria thus isolated
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