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Key Documents

284572

Sigma-Aldrich

4-Aminobenzamide

98%

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About This Item

Linear Formula:
H2NC6H4CONH2
CAS Number:
Molecular Weight:
136.15
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Assay

98%

form

solid

mp

181-183 °C (lit.)

functional group

amide

SMILES string

NC(=O)c1ccc(N)cc1

InChI

1S/C7H8N2O/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H2,9,10)

InChI key

QIKYZXDTTPVVAC-UHFFFAOYSA-N

Related Categories

Application

4-Aminobenzamide was used as a poly(ADP-ribose)polymerase (PADPRP) inhhibitor to study the death of target cells by cytotoxic effector cells using the nuclear enzyme poly(ADP-ribose)polymerase (PADPRP).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Kinetics of heparin action.
J D Shore et al.
Annals of the New York Academy of Sciences, 556, 75-80 (1989-01-01)
R J Baugh et al.
The Journal of biological chemistry, 275(37), 28826-28833 (2000-07-13)
The initiation of coagulation results from the activation of factor X by an enzyme complex (Xase) composed of the trypsin-like serine proteinase, factor VIIa, bound to tissue factor (TF) on phospholipid membranes. We have investigated the basis for the protein
P Burgman et al.
Radiation research, 119(2), 380-386 (1989-08-01)
The purpose of this study was to investigate possible involvement of poly(ADP-ribosyl)ation reactions in X-ray-induced cell killing, repair of potentially lethal damage (PLD), and formation and repair of radiation-induced DNA damage. As tools we used the inhibitors of poly(ADP-ribose)polymerase, 3-aminobenzamide
S D Ray et al.
Molecular and cellular biochemistry, 218(1-2), 27-33 (2001-05-02)
Previous studies from our laboratories have linked the protective abilities of IH636 grape seed proanthocyanidin extract (GSPE) with inactivation of anti-apoptotic gene bcl-XL, and modification of several other critical molecular targets such as DNA-damage/DNA-repair, lipid peroxidation and intracellular Ca2+ homeostasis.
Inhibition of nitric oxide induced cytotoxicity in pancreatic b-cells.
S A Brennan et al.
Biochemical Society transactions, 24(1), 73S-73S (1996-02-01)

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