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131865

Sigma-Aldrich

Tetrachlorophthalic anhydride

96%

Synonym(s):

1,3-Dioxy-4,5,6,7-tetrachloroisobenzofuran, 3,4,5,6-Tetrachlorophthalic anhydride, 4,5,6,7-Tetrachloro-1,3-isobenzofurandione, 4,5,6,7-Tetrachloroisobenzofuran-1,3-dione, Niagathal

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About This Item

Empirical Formula (Hill Notation):
C8Cl4O3
CAS Number:
Molecular Weight:
285.90
Beilstein:
211560
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

vapor pressure

0.16 mmHg ( 145 °C)

Assay

96%

form

solid

bp

371 °C (lit.)

mp

253-257 °C (lit.)

SMILES string

Clc1c(Cl)c(Cl)c2C(=O)OC(=O)c2c1Cl

InChI

1S/C8Cl4O3/c9-3-1-2(8(14)15-7(1)13)4(10)6(12)5(3)11

InChI key

AUHHYELHRWCWEZ-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

680.0 °F - closed cup

Flash Point(C)

360 °C - closed cup


Certificates of Analysis (COA)

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W Howe et al.
The Journal of allergy and clinical immunology, 71(1 Pt 1), 5-11 (1983-01-01)
We describe seven women with asthma induced by occupational exposure to an acid anhydride, tetrachlorophthalic anhydride (TCPA), an epoxy resin hardening agent. Inhalation tests with TCPA at atmospheric concentrations of less than one tenth of a manufacturer's recommended exposure limit
K M Venables et al.
The Journal of allergy and clinical immunology, 85(1 Pt 1), 55-58 (1990-01-01)
Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels of TCPA exposure. Measurements of TCPA in the test-cubicle air ranged from 1.3 to 961.1 micrograms/m3. The higher exposures provoked
W P Ridley et al.
Journal of toxicology and environmental health, 24(2), 217-227 (1988-01-01)
The capacity for induction of microsomal metabolic enzymes by tetrachlorophthalic anhydride (TCPA) was evaluated in male Sprague-Dawley rats and male CD-1 mice. The rats were orally dosed for 7 d with TCPA suspended in corn oil at 25, 100, 250
Allergic reactions to industrial chemicals.
K G McGrath et al.
Clinical immunology reviews, 2(1), 1-58 (1983-01-01)
Acid anhydrides.
A J Taylor
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 21 Suppl 1, 234-240 (1991-01-01)

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