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1118000

USP

Chloroquine phosphate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Chloroquine diphosphate salt, N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt

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About This Item

Empirical Formula (Hill Notation):
C18H26ClN3 · 2H3PO4
CAS Number:
Molecular Weight:
515.86
Beilstein:
4223142
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

Pricing and availability is not currently available.

biological source

synthetic

grade

pharmaceutical primary standard

Agency

USP

vapor pressure

<0.0000001 kPa ( 25 °C)

API family

chloroquine

form

powder

packaging

pkg of 500 mg

manufacturer/tradename

USP

storage condition

protect from light

color

yellow

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This Item
C6628PHR12581118394
grade

pharmaceutical primary standard

grade

-

grade

certified reference material, pharmaceutical secondary standard

grade

pharmaceutical primary standard

format

neat

format

-

format

neat

format

neat

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

form

powder

form

powder or crystals

form

-

form

powder

biological source

synthetic

biological source

-

biological source

synthetic

biological source

synthetic

General description

Chloroquine Phosphate is a salt of chloroquine, a 9-aminoquinoline drug that effectively inhibits viral infections in humans.[1]

Application

Chloroquine phosphate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Amodiaquine Hydrochloride
  • Amodiaquine Hydrochloride Tablets
  • Chloroquine
  • Chloroquine Phosphate
  • Chloroquine Phosphate Compounded Oral Suspension
  • Chloroquine Phosphate Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


  • Certificates of Analysis (COA)

    Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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    Determination of chloroquine and its decomposition products in various brands of different dosage forms by liquid chromatography
    Abdelrahman AN, et al.
    Journal of Pharmaceutical and Biomedical Analysis, 12(2), 205-208 (1994)
    Zilong Wang et al.
    Brain : a journal of neurology, 144(2), 665-681 (2020-12-29)
    Opioids such as morphine are mainstay treatments for clinical pain conditions. Itch is a common side effect of opioids, particularly as a result of epidural or intrathecal administration. Recent progress has advanced our understanding of itch circuits in the spinal
    Cecilia Pessoa Rodrigues et al.
    Nature communications, 12(1), 6212-6212 (2021-10-29)
    Noncommunicable diseases (NCDs) account for over 70% of deaths world-wide. Previous work has linked NCDs such as type 2 diabetes (T2D) to disruption of chromatin regulators. However, the exact molecular origins of these chronic conditions remain elusive. Here, we identify
    Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
    Vincent MJ, et al.
    Virology Journal, 2(1), 1-10 (2005)
    Chloroquine Phosphate USP Monograph
    USP43-NF38: United States Pharmacopeia and National Formulary
    United States Pharmacopeia, 39(3), 959-959 (2020)

    Protocols

    Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

    Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

    Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

    Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

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