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49055

Supelco

Parathion-methyl

PESTANAL®, analytical standard

Synonym(s):

O,O-Dimethyl O-(4-nitrophenyl) phosphorothioate, Methyl parathion

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About This Item

Empirical Formula (Hill Notation):
C8H10NO5PS
CAS Number:
Molecular Weight:
263.21
Beilstein:
8905814
EC Number:
MDL number:
UNSPSC Code:
12000000
PubChem Substance ID:

grade

analytical standard

Quality Level

product line

PESTANAL®

CofA

current certificate can be downloaded

packaging

ampule of 500 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

neat

storage temp.

room temp

SMILES string

COP(=S)(OC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C8H10NO5PS/c1-12-15(16,13-2)14-8-5-3-7(4-6-8)9(10)11/h3-6H,1-2H3

InChI key

RLBIQVVOMOPOHC-UHFFFAOYSA-N

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General description

Parathion-methyl is an organophosphate insecticide, which is extensively used for agricultural purposes. Its mode of action involves the inactivation of the enzyme acetylcholinesterase (AChE) in insects and also mammals. It undergoes degradation by soil microorganisms to yield p-nitrophenol as the product.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Flam. Liq. 3 - STOT RE 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

114.8 °F - open cup

Flash Point(C)

46 °C - open cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Absorption, distribution, metabolism and excretion of daily oral doses of [14 C] methyl parathion in hens
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Toxicology Letters, 125(1), 1-10 (2001)
Effect of paraoxon-methyl and parathion-methyl on DNA in human lymphocytes and protective action of vitamin C
Blasiak J and Kowalik J
Pest Management Science, 55(12), 1182-1186 (1999)
Jingming Gong et al.
Biosensors & bioelectronics, 39(1), 320-323 (2012-08-08)
We developed a highly sensitive flow injection/amperometric biosensor for the detection of organophosphate pesticides (OPs) using layered double hydroxides (LDHs) as the immobilization matrix of acetylcholinesterase (AChE). LDHs provided a biocompatible microenvironment to keep the bioactivity of AChE, due to
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Methyl parathion (MP) is a widely used organophosphorus pesticide that causes severe health and environmental effects. We investigated the alteration of the proteomic profile in the membrane enriched fraction of the kidneys of the scallop Mizuhopecten yessoensis exposed to low-level

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