M5942

MRS 2395

≥98% (HPLC), solid

• Synonym(s): 2,2-Dimethyl-propionic acid 3-(2-chloro-6-methylaminopurin-9-yl)-2-(2,2-dimethyl-propionyloxymethyl)-propyl ester
• Empirical Formula (Hill Notation): C₂₀H₃₀ClN₅O₄
• CAS Number: 491611-55-3
• Molecular Weight: 439.94
• MDL number: MFCD05865235
• UNSPSC Code: 12352200
• PubChem Substance ID: 329818027
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: >10 mg/mL; H₂O: insoluble
• SMILES string: CNc1nc(Cl)nc2n(CC(COC(=O)C(C)(C)C)COC(=O)C(C)(C)C)cnc12
• InChI: 1S/C20H30ClN5O4/c1-19(2,3)16(27)29-9-12(10-30-17(28)20(4,5)6)8-26-11-23-13-14(22-7)24-18(21)25-15(13)26/h11-12H,8-10H2,1-7H3,(H,22,24,25)
• InChI key: NASABYJQIYJDID-UHFFFAOYSA-N

Description

Biochem/physiol Actions

Antagonist for P2Y₁₂ purinoceptor; inhibits ADP-induced aggregation in rat platelets and antagonizes ADP-induced inhibition of cAMP in rat and human platelets in the presence of PGE1 without affecting P2Y₁ receptor-induced PLC activity in transfected astrocytoma cells.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves