M2140
1-Decanoyl-rac-glycerol
≥99%
Synonym(s):
Monocaprin
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All Photos(3)
About This Item
Empirical Formula (Hill Notation):
C13H26O4
CAS Number:
Molecular Weight:
246.34
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
biological source
synthetic (organic)
Quality Level
Assay
≥99%
form
powder
functional group
ketone
lipid type
neutral glycerides
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C(OCC(O)CO)CCCCCCCCC
InChI
1S/C13H26O4/c1-2-3-4-5-6-7-8-9-13(16)17-11-12(15)10-14/h12,14-15H,2-11H2,1H3
InChI key
LKUNXBRZDFMZOK-UHFFFAOYSA-N
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Related Categories
Application
- Novel LC/MS/MS and High-Throughput Mass Spectrometric Assays for Monoacylglycerol Acyltransferase Inhibitors.: This research presents advanced assays for screening inhibitors of monoacylglycerol acyltransferase, with implications for metabolic disease treatment. 1-Decanoyl-rac-glycerol is a key compound in the study (Qi J et al., 2017).
- Optimized reverse micelle surfactant system for high-resolution NMR spectroscopy of encapsulated proteins and nucleic acids dissolved in low viscosity fluids.: The paper describes a novel surfactant system using 1-Decanoyl-rac-glycerol, which improves the NMR spectroscopy of proteins and nucleic acids, offering better resolution and reduced viscosity (Dodevski I et al., 2014).
Biochem/physiol Actions
Monocaprin (glycerol monocaprate) is used in the development of antimicrobial disinfectants active against enveloped viruses, and certain yeast and bacteria such as candida albicans and campylobacter.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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T Kristmundsdóttir et al.
Journal of pharmaceutical sciences, 88(10), 1011-1015 (1999-10-09)
A number of medium-chain saturated and long-chain unsaturated fatty acids and their monoglycerides were tested against herpes simplex virus (HSV-1) to determine which lipids were most active during a short incubation time. The aim was to find which lipid would
Thórunn Osk Thorgeirsdóttir et al.
Acta odontologica Scandinavica, 64(1), 21-26 (2006-01-24)
Monocaprin is a 1-monoglyceride of capric acid that has antimicrobial activity against enveloped viruses, certain bacteria, and the yeast Candida albicans. Solutions containing monocaprin were formulated and tested in vitro against a number of micro-organisms, including species found in the
Halldor Thormar et al.
Applied and environmental microbiology, 72(1), 522-526 (2006-01-05)
Of 11 fatty acids and monoglycerides tested against Campylobacter jejuni, the 1-monoglyceride of capric acid (monocaprin) was the most active in killing the bacterium. Various monocaprin-in-water emulsions were prepared which were stable after storage at room temperature for many months
Thórunn O Thorgeirsdóttir et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 59(2), 333-342 (2005-01-22)
The purpose of this study was to characterize the rheological and structural properties of a pharmaceutical multicomponent hydrogel formulation. This formulation consists of a hydrogel-forming poly(acrylic acid) polymer (Carbopol 974P), microbicide (monocaprin), non-ionic surfactant (Tween 20 or Tween 40), and
J R Brown et al.
International journal of pharmaceutics, 245(1-2), 133-142 (2002-09-25)
This study explores the potential of the monoglyceride monocaprin as an enhancer of the epithelial permeability of the beta(3)-adrenoceptor agonist BTA-243, as an approach to improving the bioavailability of this drug. The permeabilities of BTA-243 and mannitol (paracellular marker) in
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