Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

L4170

Sigma-Aldrich

LDN-57444

≥98% (HPLC)

Synonym(s):

3-(O-acetyloxime), 5-chloro-1-[(2,5-dichlorophenyl)methyl]-1H-Indole-2,3-dione, C30, LDN 57444

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H11Cl3N2O3
CAS Number:
668467-91-2
Molecular Weight:
397.64
MDL number:
MFCD09037562
UNSPSC Code:
12352200
PubChem Substance ID:
329817408
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

solid

storage condition

desiccated
protect from light

solubility

DMSO: 16 mg/mL

storage temp.

2-8°C

SMILES string

CC(=O)O\N=C1/C(=O)N(Cc2cc(Cl)ccc2Cl)c3ccc(Cl)cc13

InChI

1S/C17H11Cl3N2O3/c1-9(23)25-21-16-13-7-12(19)3-5-15(13)22(17(16)24)8-10-6-11(18)2-4-14(10)20/h2-7H,8H2,1H3/b21-16-

InChI key

OPQRFPHLZZPCCH-PGMHBOJBSA-N

Biochem/physiol Actions

LDN-57444 is a potent, reversible, competitive and active site-directed inhibitor of UCHL1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Amanda J Steiman et al.
The Journal of rheumatology, 41(9), 1808-1816 (2014-08-03)
Systemic lupus erythematosus (SLE) is typically a relapsing/remitting disease. However, some patients experience prolonged remission. These patients may provide further insights into SLE pathophysiology. In this study we characterize their clinical course. Prolonged remission was defined as Systemic Lupus Erythematosus
Lorena Ruiz de Larrinaga et al.
Nutrients, 11(7) (2019-07-07)
Vegetables, once harvested and stored on supermarket shelves, continue to perform biochemical adjustments due to their modular nature and their ability to retain physiological autonomy. They can live after being harvested. In particular, the content of some essential nutraceuticals, such
Anna Wing et al.
Cancer immunology research, 6(5), 605-616 (2018-03-29)
T cells expressing chimeric antigen receptors (CART) have shown significant promise in clinical trials to treat hematologic malignancies, but their efficacy in solid tumors has been limited. Oncolytic viruses have the potential to act in synergy with immunotherapies due to
Thomas Vogl et al.
Nature communications, 9(1), 3589-3589 (2018-09-06)
Numerous synthetic biology endeavors require well-tuned co-expression of functional components for success. Classically, monodirectional promoters (MDPs) have been used for such applications, but MDPs are limited in terms of multi-gene co-expression capabilities. Consequently, there is a pressing need for new
Giulia Chitarrini et al.
Protoplasma, 254(6), 2095-2106 (2017-03-23)
Metabolic changes can occur in plants in response to abiotic stress. Extensive use of leaf discs (mechanical wounding) in studies regarding the effect on the biochemical response of the grapevine to different types of biotic stress makes it necessary to
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service