Skip to Content
Merck
All Photos(1)

Key Documents

L2752

Sigma-Aldrich

Leu-Leu

>98% (TLC), suitable for ligand binding assays

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C12H24N2O3
CAS Number:
Molecular Weight:
244.33
EC Number:
MDL number:
UNSPSC Code:
12352202
PubChem Substance ID:
NACRES:
NA.26

product name

Leu-Leu,

Assay

>98% (TLC)

Quality Level

form

powder

technique(s)

ligand binding assay: suitable

color

white to off-white

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI

1S/C12H24N2O3/c1-7(2)5-9(13)11(15)14-10(12(16)17)6-8(3)4/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t9-,10-/m0/s1

InChI key

LCPYQJIKPJDLLB-UWVGGRQHSA-N

Amino Acid Sequence

Leu-Leu

Biochem/physiol Actions

Leucylleucine (Leu-Leu) may be used to study the functionality of dileucine motifs such as the motif responsible for internalization and targeting of vesicular acetylcholine transporter and clathrin adaptors AP-1 and AP-2.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Guoqing Wang et al.
Cellular and molecular neurobiology, 41(1), 163-171 (2020-04-23)
Traditionally, hydrogen peroxide (H2O2) was formed from cellular oxidative metabolism and often viewed as toxic waste. In fact, H2O2 was a benefit messenger for neuron-glia signaling and synaptic transmission. Thus, H2O2 was a double-edged sword and neuroprotection vs. neurotoxicity produced
A van Boven et al.
Biochimie, 70(4), 535-542 (1988-04-01)
Different strains of Lactococcus lactis ssp. cremoris hydrolyze peptides at different rates while the cell-free extracts of these strains all show the same or much higher rates of hydrolysis. These observations indicate that the uptake of peptides is the rate-limiting
Yanzhen Zhou et al.
Journal of neuroinflammation, 15(1), 161-161 (2018-05-29)
Microglia-mediated neuroinflammation is recognized to mainly contribute to the pathogenesis of Parkinson's disease (PD). Tetrahydroxystilbene glucoside (TSG) has been proved to be beneficial for health with a great number of pharmacological properties. We examined the effects of TSG against dopamine
Lingling Zhang et al.
Oncogene, 39(49), 7196-7208 (2020-10-11)
Metastasis is responsible for the death of most breast cancer patients. Robo1 has been implicated as a tumor suppressor for various cancers including breast cancer. However, it is not well understood how Robo1 expression is regulated during tumorigenesis. In this
Diego Sbardella et al.
Biochemical pharmacology, 177, 113977-113977 (2020-04-17)
Citicoline or CDP-choline is a drug, made up by a cytidine 5'-diphosphate moiety and choline, which upon adsorption is rapidly hydrolyzed into cytidine 5'-diphosphate and choline, easily bypassing the blood-brain barrier. Once in the brain, these metabolites are used to

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service