Skip to Content
Merck
All Photos(2)

Key Documents

A7736

Sigma-Aldrich

Albumin human

recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)

Synonym(s):

Albagen, rHSA

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C2936H4624N786O889S41
CAS Number:
Molecular Weight:
66471.53
EC Number:
MDL number:
UNSPSC Code:
12352202
NACRES:
NA.25

biological source

human

Quality Level

recombinant

expressed in Pichia pastoris

Assay

≥90% (agarose gel electrophoresis)

form

lyophilized powder

mol wt

monomer ~67 kDa

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

storage temp.

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Gene Information

human ... ALB(213)

Looking for similar products? Visit Product Comparison Guide

Application

This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.

Biochem/physiol Actions

Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.

Physical properties

Construct with a single deletion of Asp from the N-terminus to create a hypoallergenic construct. Structural equivalence to native albumin confirmed x-ray crystallography. The Asp deletion eliminates an important antigenic determinant by eliminating the principal copper and nickel binding site of albumin. The first three residues of human albumin are considered non-structural. Also blocked at Cys34 to improve stability, monomer content and homogeneity.

Other Notes

View more information on human serum albumin.

Legal Information

Albagen is a trademark of Albumin Therapeutics, LLC.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mika Suga et al.
Methods in molecular biology (Clifton, N.J.), 1965, 35-48 (2019-05-10)
Cranial neural crest cells (NCCs) migrate to the branchial arches and give rise to the majority of cranial mesenchyme that eventually differentiates into odontoblasts, cartilage, craniofacial bone, and connective tissue; a subset of these cells differentiate into cranial ganglia. Here
Insights into the effects of N-glycosylation on the characteristics of the VC1 domain of the human receptor for advanced glycation end products (RAGE) secreted by Pichia pastoris.
Degani, et al.
Glycoconjugate Journal, 36, 27-38 (2020)
Francesco Scavello et al.
Aging, 11(6), 1648-1663 (2019-03-25)
The receptor for advanced glycation end-products (RAGE) recognizes several ligands involved in inflammatory diseases. Two circulating soluble isoforms exist: esRAGE derived from alternative splicing and cRAGE generated by the membrane-bound RAGE (FL-RAGE) proteolysis. Together, esRAGE and cRAGE constitute sRAGE and
Jay Jagannathan et al.
Journal of neurosurgery, 109(3), 547-552 (2008-09-02)
Convection-enhanced delivery (CED) is increasingly used to investigate new treatments for central nervous system disorders. Although the properties of CED are well established in normal gray and white matter central nervous system structures, the effects on drug distribution imposed by
Kah Yong Tan et al.
Cytotherapy, 17(8), 1152-1165 (2015-07-04)
Mesenchymal stromal cells (MSCs) are being investigated as potential cell therapies for many different indications. Current methods of production rely on traditional monolayer culture on tissue-culture plastic, usually with the use of serum-supplemented growth media. However, the monolayer culturing system

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service