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Key Documents

A2787

Sigma-Aldrich

N-Acetyl-D-galactosamine–Agarose

saline suspension

Synonym(s):

N-Acetyl Galactosamine

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About This Item

MDL number:
UNSPSC Code:
23151817
NACRES:
NA.56

biological source

plant

Quality Level

form

saline suspension

technique(s)

affinity chromatography: suitable

matrix

cross-linked 4% beaded agarose

matrix activation

epoxy

matrix attachment

6-hydroxy

matrix spacer

12 atoms

capacity

≥6 mg/mL binding capacity (lectin from Glycine max)

suitability

suitable for chromatography

storage temp.

2-8°C

Application

N-Acetyl-D-galactosamine is an agarose used in affinity chromatography, protein chromatography and in carbohydrate matrices. N-Acetyl-D-galactosamine has been used to study periodontal disease and to facilitate the design of potent small-molecule ice recrystallization inhibitors. N-Acetyl-D-galactosamine has also been used to demonstrate a molecular shuttle between extracellular and cytoplasmic space allows for monitoring of GAG biosynthesis.

Physical form

Suspension in 0.5 M NaCl containing preservative.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A new histochemical approach for studying sperm cell surfaces.
Ngo, L., et al.
Acta Histochemica, 106(1), 21-28 (2003)
Hiroko Hoshi et al.
Biochimica et biophysica acta, 1820(9), 1391-1398 (2012-01-24)
Cell surface proteoglycans play vital functional roles in various biological processes such as cell proliferation, differentiation, adhesion, inflammation, immune response, sustentation of cartilage tissue and intensity of tissues. We show here that serglycin-like synthetic glycopeptides function efficiently as a molecular
Anna K Balcerzak et al.
Bioorganic & medicinal chemistry letters, 22(4), 1719-1721 (2012-01-24)
The β-d-galactosyl-(1,3)-α-N-acetyl-d-galactosamine disaccharide is present in antifreeze glycoproteins (AFGPs). Analogs of this disaccharide including the β-linked (1,3)-, (1,4)-, and (1,6)-galactosyl-N-acetyl galactosamine and the β-(1,3)-galactosyl-galactoside were synthesized and evaluated for ice recrystallization inhibition (IRI) activity. The results from this study demonstrate
Reynald Tremblay et al.
Transgenic research, 20(2), 345-356 (2010-06-19)
Soybean agglutinin (SBA) is a specific N-acetylgalactosamine-binding plant lectin that can agglutinate a wide variety of cells. SBA has great potential for medical and biotechnology-focused applications, including screening and treatment of breast cancer, isolation of fetal cells from maternal blood
Jining Liu et al.
Xenotransplantation, 10(2), 149-163 (2003-02-18)
Hyperacute organ xenograft rejection can be prevented by removing anti-pig antibodies by extracorporeal absorption prior to transplantation. A novel recombinant absorber of anti-pig antibodies was developed by fusing the cDNA encoding the extracellular part of a mucin-type protein, P-selectin glycoprotein

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