85451

β-Sitosterol

≥70%

• Synonym(s): α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, 24α-Ethylcholesterol, 5-Stigmasten-3β-ol
• Empirical Formula (Hill Notation): C₂₉H₅₀O
• CAS Number: 83-46-5
• Molecular Weight: 414.71
• Beilstein: 1916165
• EC Number: 201-480-6
• MDL number: MFCD00003631
• UNSPSC Code: 12352211
• PubChem Substance ID: 329769380
• NACRES: NA.77

Properties

• biological source: plant
• Quality Level: 200
• Assay: ≥70%
• form: powder
• impurities: campesterol and β-sitostanol, residual
• mp: 136-140 °C (lit.)
• functional group: hydroxyl
• SMILES string: O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CC[C@H](C(C)C)CC
• InChI: 1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
• InChI key: KZJWDPNRJALLNS-VJSFXXLFSA-N

Description

Application

β-Sitosterol was used to supplement diet of mice to study its effect on body mass accumulation.

Biochem/physiol Actions

β-Sitosterol is a plant sterol that has hypocholesterolemic activity. Only 5% of β-Sitosterol is absorbed by humans. It is hypothesized that the cholesterol-lowering activity is by competing cholesterol for uptake by the cells or by interfering with the esterification of cholesterol. β-Sitosterol is reported to reduce the incidence of colon tumors.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves