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Z2251

Sigma-Aldrich

Zinquin ethyl ester

≥95% purity (HPLC), solid

Synonym(s):

2-Methyl-8-[(4-methylphenyl)sulfonylamino]-6-(ethyloxycarbonylmethyloxy)quinoline

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About This Item

Empirical Formula (Hill Notation):
C21H22N2O5S
Molecular Weight:
414.47
MDL number:
MFCD00797629
UNSPSC Code:
12171500
PubChem Substance ID:
329831605
NACRES:
NA.47

product name

Zinquin ethyl ester, ≥95% (HPLC), solid

Assay

≥95% (HPLC)

form

solid

color

off-white

solubility

DMSO: soluble
methanol: soluble

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

CCOC(=O)COc1cc(NS(=O)(=O)c2ccc(C)cc2)c3nc(C)ccc3c1

InChI

1S/C21H22N2O5S/c1-4-27-20(24)13-28-17-11-16-8-7-15(3)22-21(16)19(12-17)23-29(25,26)18-9-5-14(2)6-10-18/h5-12,23H,4,13H2,1-3H3

InChI key

KCASTCXJTDRDFT-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

Used to detect zinc in cells by UV fluorescence.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV0053
MKCS7330
MKCP9144
MKCM8643
MKCM1106

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Abrogation of Nuclear Factor-?B Activation Is Involved in Zinc Inhibition of Lipopolysaccharide-Induced Tumor Necrosis Factor-a Production and Liver Injury
Zhanxiang Z
The American Journal of Pathology (2004)
Yu Gong et al.
Journal of applied toxicology : JAT, 37(8), 895-901 (2016-11-20)
Recent studies showed that ZnO nanoparticles (NPs) might induce the toxicity to human endothelial cells. However, little is known about the interaction between ZnO NPs and circulatory components, which is likely to occur when NPs enter the blood. In this
Sarah R Aldhaheri et al.
Free radical biology & medicine, 112, 445-451 (2017-08-29)
In light of the recent lead contamination of the water in Flint, Michigan and its potential adverse outcomes, much research and media attention has turned towards the safety profile of commonly used chelators. Dimercapto-1-propanesulfonic acid (DMPS) typically used in the
Correlation of apoptosis with change in intracellular labile Zn(ll) using
Zinquin [(2-methyl-8-p-toluenesulphonamido-6-quinolyloxy)acetic acid],
a new specific fluorescent probe for Zn(ll)
Peter D
The Biochemical Journal (1993)
Xianqiang Li et al.
Toxicology mechanisms and methods, 28(7), 520-528 (2018-04-27)
It is recently shown that biological macromolecules in food could interact with nanoparticles (NPs) and consequently change the biological effects of NPs. In this study, the interactions between ZnO NPs with or without hydrophobic surface coating and bovine serum albumin
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