Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

LM2144

Avanti

Sphingosine-1-Phosphate (d17:1)

Avanti Research™ - A Croda Brand

Synonym(s):

heptadeca-sphing-4-enine-1-phosphate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C17H36NO5P
CAS Number:
474923-27-8
Molecular Weight:
365.45
UNSPSC Code:
12352211
NACRES:
NA.25

form

ethanol solution

packaging

pkg of 1 × 1 mL (LM2144-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

~10 μg/mL (Refer to C of A for lot specific concentration.)

application(s)

lipidomics
metabolomics

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCCCCCCCCC/C=C/[C@@]([H])(O)[C@]([NH3+])([H])COP([O-])(O)=O

InChI

1S/C17H36NO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(19)16(18)15-23-24(20,21)22/h13-14,16-17,19H,2-12,15,18H2,1H3,(H2,20,21,22)/b14-13+/t16-,17+/m0/s1

InChI key

VITGNIYTXHNNNE-LHMZYYNSSA-N

General description

Sphingosine-1-phosphate (S1P) is a sphingolipid found in yeast, plants and mammals and is produced in endothelial cells. It is a cellular metabolite and signalling lipid in mammalian cells. S1P is synthesized by sphingosine kinases from sphingosine. It is a high affinity ligand for sphingosine-1-phosphate receptor (S1P1-5).

Biochem/physiol Actions

Sphingosine 1-phosphate (S1P) plays a vital role as a secondary messenger in physiological processes. It is implicated in the pathogenesis of osteoporosis, cancer, atherosclerosis and diabetes. S1P regulates skin dendritic cells and keratinocytes

Packaging

2 mL Amber Glass Sealed Ampule (LM2144-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Statements

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

55.4 °F - closed cup

Flash Point(C)

13.0 °C - closed cup

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Sorry, we don't have COAs for this product available online at this time.

If you need assistance, please contact Customer Support.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 2

1 of 2

Sphingosine 1-phosphate ≥98.0% (TLC)

Sigma-Aldrich

73914

Sphingosine 1-phosphate

Sphingosine-1-Phosphate (d20:1) Avanti Research™ - A Croda Brand 860662P, powder

Avanti

860662P

Sphingosine-1-Phosphate (d20:1)

High-Throughput Assays to Measure Intracellular Ca2+ Mobilization in Cells that Express Recombinant S1P Receptor Subtypes
Valentine WJ and Tigyi G
Methods in Molecular Biology, 77-87 (2012)
Sphingosine-1-phosphate signaling and its role in disease
Maceyka M, et al.
Trends in Cell Biology, 22(1), 50-60 (2012)
Sphingosine-1-phosphate as signaling molecule in the skin
Japtok L, et al.
Allergo journal international, 23(2), 54-59 (2014)
Sphingosine-1-phosphate: an enigmatic signalling lipid
Spiegel S and Milstien S
Nature Reviews in Molecular and Cell Biology, 4(5), 397-397 (2003)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service