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D161802

Sigma-Aldrich

N,N′-Dimethylhydrazine dihydrochloride

98%

Synonym(s):

1,2-Dimethylhydrazine dihydrochloride, N,N′-Dimethylhydrazine (sym.) dihydrochloride

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About This Item

Linear Formula:
CH3NHNHCH3 · 2HCl
CAS Number:
306-37-6
Molecular Weight:
133.02
Beilstein:
3905684
EC Number:
206-183-5
MDL number:
MFCD00012522
UNSPSC Code:
12352100
PubChem Substance ID:
24893498
NACRES:
NA.22

Quality Level

200

Assay

98%

form

crystals

mp

167-169 °C (dec.) (lit.)

SMILES string

Cl[H].Cl[H].CNNC

InChI

1S/C2H8N2.2ClH/c1-3-4-2;;/h3-4H,1-2H3;2*1H

InChI key

WLDRFJDGKMTPPV-UHFFFAOYSA-N

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Biochem/physiol Actions

Induces colon cancer in rats and mice.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 1B

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC7909
BCBV0675
STBB6282
STBB6073
BCBS6347V

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Vijay L Kumar et al.
Drug development research, 80(8), 1089-1097 (2019-09-01)
Anti-inflammatory drugs are well known to reduce the risk of colon cancer and prophylactic use of such agents is gaining acceptance as a cancer prevention therapy. As artesunate, an antimalarial drug, has been shown to exhibit chemopreventive properties, the present
Reema Narayan et al.
Carbohydrate polymers, 261, 117893-117893 (2021-03-27)
Glycosylated pH-sensitive mesoporous silica nanoparticles (MSNs) of capecitabine (CAP) were developed for targeting colorectal cancer. The MSNs possessed an average pore diameter of 8.12 ± 0.43 nm, pore volume of 0.73 ± 0.21 cm3/g, and particle size of 245.24 ±
Preety Ghanghas et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 78, 239-247 (2016-02-24)
Non-steroidal anti-inflammatory drugs (NSAIDs) are emerging as novel chemopreventive agents against a variety of cancers owing to their capability in blocking the tumor development by cellular proliferation and by promoting apoptosis. Inflammation is principal cause of colon carcinogenesis. A missing
Luciana Azevedo et al.
Journal of the science of food and agriculture, 99(2), 624-631 (2018-06-29)
Camu-camu (Myrciaria dubia) is a typical Amazonian fruit and has high antioxidant capacity due to its high levels of vitamin C and phenolic compounds. This study aimed to determine the phytochemicals, antioxidant capacity and antimutagenic effects of camu-camu fruits with
Leila Kaeid Sharaf et al.
Nutrition and cancer, 70(6), 946-955 (2018-09-06)
Epidemiological and experimental observations have shown that nonsteroidal anti-inflammatory drugs especially selective cyclooxygenase-2 (COX-2) inhibitors and probiotics reduce the incidence risk of colon cancer. Therefore, the present study was designed to assess the prophylactic potentials of probiotics (Lactobacillus acidophilus and
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