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Key Documents

D124001

Sigma-Aldrich

3,5-Diiodosalicylic acid

99%

Synonym(s):

2-Hydroxy-3,5-diiodobenzoic acid, 3,5-Diiodo-2-hydroxybenzoic acid

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About This Item

Linear Formula:
I2C6H2(OH)CO2H
CAS Number:
Molecular Weight:
389.91
Beilstein:
2615358
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

99%

form

powder

mp

220-230 °C (dec.) (lit.)

SMILES string

OC(=O)c1cc(I)cc(I)c1O

InChI

1S/C7H4I2O3/c8-3-1-4(7(11)12)6(10)5(9)2-3/h1-2,10H,(H,11,12)

InChI key

DHZVWQPHNWDCFS-UHFFFAOYSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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D Restrepo et al.
The Journal of general physiology, 100(5), 825-846 (1992-11-01)
We have developed a new test to differentiate between ping-pong and simultaneous mechanisms for tightly coupled anion exchange. This test requires the use of a dead-end reversible noncompetitive inhibitor. As an example, we have applied the test to the anion
L Simchowitz et al.
The American journal of physiology, 261(5 Pt 1), C906-C915 (1991-11-01)
Organotin derivatives represent a class of artificial ionophores that mediate Cl(-)-OH- exchange and thereby facilitate the chemical equilibrium distribution of Cl- and H+ across biological membranes. Imposing different pH and Cl- gradients by varying extracellular pH (pHo) and extracellular [Cl-]
D Riendeau et al.
Molecular and cellular biochemistry, 71(1), 45-52 (1986-06-01)
Lithium diiodosalicylate (LIS) was used to selectively solubilize proteins from purified intestinal brush border membrane vesicles. Incubation of the vesicles with increasing concentrations of LIS resulted in the progressive release of proteins with total disruption of the membranes being obtained
Nuclear frameworks: concepts and operational definitions.
N Stuurman et al.
Cell biology international reports, 16(8), 837-852 (1992-08-01)
P Belgrader et al.
Journal of cell science, 98 ( Pt 3), 281-291 (1991-03-01)
Different agents have been employed to extract the histones and other soluble components from isolated HeLa S3 nuclei during nuclear matrix isolation. We report that 0.2M (NH4)2SO4 is a milder extracting agent than NaCl and LIS (lithium 3,5-diiodosalicylate), on the

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