Skip to Content
Merck
All Photos(1)

Key Documents

90303

Sigma-Aldrich

4-(Boc-amino)butyl bromide

technical, ≥90% (AT)

Synonym(s):

Carbamic acid, (4-bromobutyl)-, 1,1-dimethylethyl ester, tert-Butyl N-(4-bromobutyl)carbamate

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
Br(CH2)4NHCO2C(CH3)3
CAS Number:
Molecular Weight:
252.15
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

Pricing and availability is not currently available.

grade

technical

Quality Level

Assay

≥90% (AT)

form

liquid

reaction suitability

reagent type: cross-linking reagent

impurities

~5% 1-boc-pyrrolidine

functional group

Boc
amine
bromo

storage temp.

2-8°C

SMILES string

BrCCCCNC(OC(C)(C)C)=O

InChI

1S/C9H18BrNO2/c1-9(2,3)13-8(12)11-7-5-4-6-10/h4-7H2,1-3H3,(H,11,12)

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
1009191540415302
Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

reaction suitability

reagent type: cross-linking reagent

reaction suitability

reagent type: cross-linking reagent, reagent type: linker

reaction suitability

reagent type: cross-linking reagent

reaction suitability

reagent type: cross-linking reagent

storage temp.

2-8°C

storage temp.

-

storage temp.

-

storage temp.

2-8°C

form

liquid

form

-

form

-

form

-

grade

technical

grade

-

grade

-

grade

-

Application

4-(Boc-amino)butyl bromide can be used:
  • For the synthesis of N-Boc-aminoalkoxyphenyl derivatives, precursor to pharmacophore elements for the treatment of glaucoma.[1]
  • For the synthesis of various aloperine derivatives with potential application as anti-HIV agents.[2]
  • For the modification of 4,5,6,7-tetrabromobenzotriazole (TBB) derivatives to generate improved CK2 inhibitors.[3]

Other Notes

Building block for the synthesis of natural products and biologically active compounds.[4][5]

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

Eye Dam. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

  • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Structure Optimization of Aloperine Derivatives as HIV-1 Entry Inhibitors.
    Dang Z, et al.
    ACS Medicinal Chemistry Letters, 8(11), 1199-1203 (2017)
    Synthesis, biological activity and structural study of new benzotriazole-based protein kinase CK2 inhibitors.
    Swider R, et al.
    Royal Society of Chemistry Advances, 5(89), 72482-72494 (2015)
    Identification of bivalent ligands with melatonin receptor agonist and fatty acid amide hydrolase (FAAH) inhibitory activity that exhibit ocular hypotensive effect in the rabbit.
    Spadoni G, et al.
    Journal of medicinal chemistry, 61(17), 7902-7916 (2018)
    D.L. Selwood et al.
    Journal of Medicinal Chemistry, 4, 78-78 (2001)
    H. Ina et al.
    The Journal of Organic Chemistry, 61, 1023 -1023 (1995)

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service