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705993

Sigma-Aldrich

3-epi-25-Hydroxyvitamin D3

98% (CP)

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About This Item

Empirical Formula (Hill Notation):
C27H44O2
CAS Number:
73809-05-9
Molecular Weight:
400.64
MDL number:
MFCD11656130
UNSPSC Code:
12352205
PubChem Substance ID:
329762603
NACRES:
NA.24

Quality Level

200

Assay

98% (CP)

form

powder

technique(s)

mass spectrometry (MS): suitable

color

white to off-white

mass shift

M+3

storage temp.

−20°C

SMILES string

C[C@@]12[C@](CC[C@]2([H])[C@@H](CCCC(C)(O)C)C)([H])/C(CCC1)=C/C=C3C[C@H](O)CCC/3=C

InChI

1S/C27H44O2/c1-19-10-13-23(28)18-22(19)12-11-21-9-7-17-27(5)24(14-15-25(21)27)20(2)8-6-16-26(3,4)29/h11-12,20,23-25,28-29H,1,6-10,13-18H2,2-5H3/b21-11+,22-12-/t20-,23-,24-,25+,27-/m1/s1

InChI key

JWUBBDSIWDLEOM-UEGFJKGBSA-N

Application

3-epi-25-Hydroxyvitamin D3 is also known as 3-epi-25(OH)D3. It is a metabolite of vitamin D3 formed in the liver. 3-epi-25(OH)D3 is used as a biomarker to determine the status of vitamin D in the body. It can be also employed as an analytical standard to measure the concentration of 3-epi-25(OH)D3 molecules in human serum.

Packaging

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
To best serve customer requests, each order is packaged and shipped on demand approximately 2 weeks after receipt of an order. If you have questions regarding availability and price, please contact the Stable Isotope Customer Service Group at 937-859-1808 (1-800-448-9760 for US & Canada) or email us at isosales@sial.com.

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Product No.
Description
Pricing

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Statements

H301 + H311,H330,H372

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - STOT RE 1 Oral

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MBBD4488
MBBD2162
MBBC6999
MBBC5952
MBBC2745

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Andrzej Slominski et al.
The Journal of clinical endocrinology and metabolism, 98(2), E298-E303 (2013-01-09)
There is no effective treatment for systemic sclerosis and related fibrosing diseases. Recently the action of CYP11A1 on vitamin D(3) was shown to produce biologically active 20S-hydroxyvitamin D [20(OH)D(3)] and 20,23(OH)(2)D(3), 20,22(OH)(2)D(3), and 17,20,23(OH)(3)D(3). Because 20(OH)D(3) is noncalcemic (nontoxic) in
Alex Aregbesola et al.
Journal of epidemiology and community health, 67(6), 533-536 (2013-04-19)
Vitamin D has been suggested to have a role in infection defence and on the immune system. We therefore investigated the effect of serum 25-hydroxyvitamin D₃ (25(OH)D₃) on the risk of incident hospitalised pneumonia in an ageing general population in
P V Pradeep et al.
Journal of postgraduate medicine, 59(1), 4-8 (2013-03-26)
No single factor can predict the occurrence of post total thyroidectomy (TT) hypocalcemia. This study was conducted to look at various factors usually implicated in post TT clinically significant hypocalcemia (CSH) and to develop a scoring system using a combination
Yosef Dror et al.
The Journal of clinical endocrinology and metabolism, 98(5), 2160-2167 (2013-03-28)
Low serum calcidiol has been associated with multiple comorbidities and mortality but no "safe" range has been found for the upper concentration. We aim to establish the upper threshold of serum calcidiol, beyond which there is an increased risk for
3-epi-25 hydroxyvitamin D concentrations are not correlated with age in a cohort of infants and adults
Strathmann FG, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 413(1-2), 203-206 (2012)
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Method Optimization for LC-MS Analysis of Vitamin D Metabolite Critical Pairs in Serum

Using HybridSPE-Phospholipid, Ascentis Express, and Other LC-MS Workflow Components

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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