524417
3,5-Dinitro-o-toluamide
98%
Synonym(s):
2-Methyl-3,5-dinitrobenzamide
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About This Item
Linear Formula:
(O2N)2C6H2(CH3)CONH2
CAS Number:
Molecular Weight:
225.16
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Assay
98%
mp
170-180 °C (lit.)
functional group
amide
nitro
SMILES string
Cc1c(cc(cc1[N+]([O-])=O)[N+]([O-])=O)C(N)=O
InChI
1S/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
InChI key
ZEFNOZRLAWVAQF-UHFFFAOYSA-N
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General description
Water solubility of 3,5-Dinitro-o-toluamide (3,5-DNoTAME) is 447.5mg/L. It affords 3-amino-5-nitro-o-toluamide, via biological reduction. 3,5-DNoTAME also forms colored complexes on reaction with various diamines and organic solvents.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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J F Ryley et al.
Parasitology, 73(3), 287-309 (1976-12-01)
Features of the anticoccidial activity of nicarbazin, amprolium, zoalene, sulphadimidine, diaveridine, Darvisul, spiramycin, chloramphenicol and oxytetracycline have been re-investigated both in vivo and in cell culture using Eimeria tenella. Of the drugs studied, only spiramycin was appreciably coccidiocidal, although nicarbazin
Determination of 3,5-dinitro-o-toluamide in feedstuffs and pre-mixes.
M Severijnen et al.
The Analyst, 100(1192), 482-484 (1975-07-01)
O W Parks
Journal of AOAC International, 76(3), 698-701 (1993-05-01)
3-Amino-5-nitro-o-toluamide and 5-amino-3-nitro-o-toluamide, the principal metabolites in the tissues of chickens fed a diet containing Zoalene (3,5-dinitro-o-toluamide), were shown to deplete in frozen liver tissues stored up to 1 year at -20 degrees C, but not at -70 degrees C.
Determination of 3,5-dinitro-o-toluamide in poultry feedstuffs and pre-mixes by high-performance liquid chromatography.
I W Burns et al.
The Analyst, 105(1250), 509-512 (1980-05-01)
Coccidiostat toxicity.
I R Cameron et al.
The Veterinary record, 111(13), 307-307 (1982-09-25)
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