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51030

Sigma-Aldrich

Guanine hydrochloride

≥99.0%

Synonym(s):

2-Amino-6-hydroxypurine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C5H5N5O · HCl
CAS Number:
Molecular Weight:
187.59
Beilstein:
4159901
EC Number:
MDL number:
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥99.0%

form

powder

ign. residue

≤0.05%

loss

≤3.0% loss on drying

mp

≥300 °C

storage temp.

2-8°C

SMILES string

Cl.NC1=Nc2[nH]cnc2C(=O)N1

InChI

1S/C5H5N5O.ClH/c6-5-9-3-2(4(11)10-5)7-1-8-3;/h1H,(H4,6,7,8,9,10,11);1H

InChI key

IBAOFQIOOBQLHE-UHFFFAOYSA-N

General description

Guanine hydrochloride is the hydrochloride salt of the purine base, guanine. It is a component of basal medium.

Application

Guanine hydrochloride may be used in the synthesis of Na10[Pt2(μ-PO4)4(C5H3N5O)2].22H2O.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Dhanashree Selvan et al.
ACS catalysis, 9(7), 5847-5859 (2019-07-26)
We report the construction of an artificial hydrogenase (ArH) by reengineering a Cu storage protein (Cspl) into a Ni-binding protein (NBP) employing rational metalloprotein design. The hypothesis driven design approach involved deleting existing Cu sites of Csp1 and identification of
Synthesis and X-ray structure of Na10[Pt2(?-PO4)4(C5H3N5O)2].22H2O, a complex with doubly deprotonated guanine anions coordinated to diplatinum(III).
El-Mehdawi R, et al.
Inorganic Chemistry, 25(20), 3714-3716 (1986)
Kamila Mustafina et al.
ACS synthetic biology, 9(1), 19-25 (2019-12-11)
Self-cleaving ribozymes engineered to be activated or inhibited by a small molecule binding to an RNA aptamer inserted within a ribozyme (aptazymes) have proven to be useful for controlling gene expression in living cells. In mammalian cells, an aptazyme embedded
The estimation of guanine and xanthine.
Hitchings GH.
The Journal of Biological Chemistry, 139(2), 843-854 (1941)
A factor required for the growth of Leuconostoc citrovorum.
H E SAUBERLICH et al.
The Journal of biological chemistry, 176(1), 165-173 (1948-10-01)

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