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Assay
98%
mp
153 °C (dec.) (lit.)
functional group
amine
hydrazine
thiourea
storage temp.
2-8°C
SMILES string
CN(C)C(=S)NN
InChI
1S/C3H9N3S/c1-6(2)3(7)5-4/h4H2,1-2H3,(H,5,7)
InChI key
FCPHVJQWZFNNKD-UHFFFAOYSA-N
General description
4,4-Dimethyl-3-thiosemicarbazide is alkyl derivative of thiosemicarbazide. Structure of 4,4-dimethyl-3-thiosemicarbazide in solution has been investigated by NMR and in solid state by IR and X-ray crystallographic methods.
Application
4,4-Dimethyl-3-thiosemicarbazide may be employed as chemical additive to investigate the corrosion inhibition of mild steel in acidic conditions.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Biosensors & bioelectronics, 110, 110-117 (2018-04-01)
Enzyme mimics have been developed for bioassay of nucleic acids, with some of them involving complicated labeling. Herein, we report a label-free bioassay for ultrasensitive electronic determination of microRNA at an ultralow concentration based on target-triggered long-range self-assembly DNA-based hybridization
Metallomics : integrated biometal science, 8(12), 1255-1265 (2016-11-15)
A comparative study between two bisthiosemicarbazones, 2,3-butanedione bis(4,4-dimethyl-3-thiosemicarbazone) and 2,3-butanedione bis(2-methyl-3-thiosemicarbazone), and their copper(ii) complexes is reported. The four compounds have been tested on a leukemia cell line U937 (p53-null) and on an adenocarcinoma cell line A549. The study includes
Molecular dynamics and quantum chemical calculation studies on 4, 4-dimethyl-3-thiosemicarbazide as corrosion inhibitor in 2.5 MH< sub> 2</sub> SO< sub> 4</sub>.
Materials Chemistry and Physics, 129(1), 660-665 (2011)
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry (2018-07-15)
Copper 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide complex (CuHQTS) is a copper complex with strong anticancer activity against cisplatin-resistant neuroblastoma and prostate cancer cells in vitro by cell proliferation assay or fluorescent microscopic imaging. This study aimed to evaluate anti-prostate cancer activity of CuHQTS in
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