257443
Fluoroacetonitrile
98%
Synonym(s):
2-Fluoroacetonitrile, Fluoromethyl cyanide, Monofluoroacetonitrile
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About This Item
Linear Formula:
FCH2CN
CAS Number:
Molecular Weight:
59.04
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
98%
form
liquid
refractive index
n20/D 1.333 (lit.)
bp
79-80 °C (lit.)
density
1.061 g/mL at 25 °C (lit.)
functional group
fluoro
nitrile
SMILES string
FCC#N
InChI
1S/C2H2FN/c3-1-2-4/h1H2
InChI key
GNFVFPBRMLIKIM-UHFFFAOYSA-N
Application
Fluoroacetonitrile has been used in preparation of:
- 2-fluoromethyl-4,4,6-trimethyl-1,3-oxazine
- α-fluorinated acetophenone
- 2-amino-2-fluoromethyl-3-pentenenitrile, a key intermediate in the synthesis of 2,5-diamino-2-fluoromethyl-3(E)-pentenoic acid
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
6.8 °F - closed cup
Flash Point(C)
-14 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Preparative flow techniques. 2. Grignard addition reaction on fluoroaceto-nitrile: Synthesis of 2-amino-2-fluoromethyl-3-pentenenitrile.
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Journal of Fluorine Chemistry, 50(2), 243-249 (1990)
2-Fluoromethyl-4, 4, 6-trimetiiyl-1, 3-oxasine as a new reagent for the preparation of a-fluoroaldehydes.
Patrick TB, et al.
Tetrahedron Letters, 31(2), 179-182 (1990)
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