15420
Boc-Gly-OH
≥99.0% (T), for peptide synthesis
Synonym(s):
N-(tert-Butoxycarbonyl)glycine, Boc-glycine
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About This Item
Linear Formula:
(CH3)3COCONHCH2COOH
CAS Number:
Molecular Weight:
175.18
Beilstein:
1101514
EC Number:
MDL number:
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.22
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product name
Boc-Gly-OH, ≥99.0% (T)
Quality Level
Assay
≥99.0% (T)
form
powder or crystals
reaction suitability
reaction type: Boc solid-phase peptide synthesis
ign. residue
≤0.05%
mp
86-89 °C (lit.)
86-89 °C
application(s)
peptide synthesis
SMILES string
CC(C)(C)OC(=O)NCC(O)=O
InChI
1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)
InChI key
VRPJIFMKZZEXLR-UHFFFAOYSA-N
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Application
Boc-Gly-OH can be used:
- For the esterification reaction to synthesize N-Boc amino acid esters for peptide chemistry.
- For the synthesis of tripeptide H-Gly-Pro-Glu-OH, analogs of neuroprotective drugs.
- As a promoter for the allylation of hydrazones and isatin.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The catabolism of the 14C-labelled pentagastrin was investigated in rats. The following results were found: -- the labelled BOC-glycine fragment is split off the pentagastrin in the small intestine -- it is absorbed through the intestinal wall, and -- enters
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