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T4057

Sigma-Aldrich

Tyrphostin AG 1296

≥98%

Synonym(s):

6,7-Dimethoxy-2-phenylquinoxaline

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About This Item

Empirical Formula (Hill Notation):
C16H14N2O2
CAS Number:
146535-11-7
Molecular Weight:
266.29
MDL number:
MFCD00270913
UNSPSC Code:
12352200
PubChem Substance ID:
329826783

Assay

≥98%

form

powder

solubility

methylene chloride: soluble 10 mg/mL
DMSO: soluble

storage temp.

2-8°C

SMILES string

COc1cc2ncc(nc2cc1OC)-c3ccccc3

InChI

1S/C16H14N2O2/c1-19-15-8-12-13(9-16(15)20-2)18-14(10-17-12)11-6-4-3-5-7-11/h3-10H,1-2H3

InChI key

QNOXYUNHIGOWNY-UHFFFAOYSA-N

Biochem/physiol Actions

Studies have reported that phosphorylation of tyrosine 857 in PDGF β-receptor is the most susceptible to inhibition by tyrphostin AG 12962.
Selective inhibitor of platelet-derived growth factor (PDGF) receptor protein.

Preparation Note

Tyrphostin AG 1296 is soluble in methylene chloride at 10 mg/ml and is also soluble in DMSO.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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