SRP6161

FGF-7 human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

• Synonym(s): Fibroblast growth factor 7, HBGF-7, Heparin-binding growth factor 7, KGF, Keratinocyte growth factor
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in human cells
• Assay: ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: (17 and 30 kDa, monomer, glycosylated)
• packaging: pkg of 10 μg
• technique(s): cell culture | mammalian: suitable
• NCBI accession no.: P21781
• UniProt accession no.: P21781
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... FGF7(2252)

Description

General description

Fibroblast growth factor-7 (FGF-7) is a member of the fibroblast growth factor family. FGF family members possess broad mitogenic and cell survival activities. The gene encoding this protein is localized on human chromosome 15q21.1.

Biochem/physiol Actions

Fibroblast growth factor (FGF) family members are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. This protein associates with and activates fibroblast growth factor receptors (FGFRs). Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, re-epithelialization of wounds, hair development and early lung organogenesis.

Physical form

Lyophilized from a PBS solution.

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable