SRP6153

Activin A human

recombinant, expressed in human cells, ≥95% (SDS-PAGE)

• Synonym(s): FRP, FSH-releasing protein, Inhibin beta A
• CAS Number: 104625-48-1
• UNSPSC Code: 12352202
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in human cells
• Assay: ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: 25 kDa (homodimer, non-glycosylated)
• packaging: pkg of 10 μg
• NCBI accession no.: P08476
• shipped in: dry ice
• storage temp.: −70°C
• InChI: 1S/C27H34O3/c1-27-16-15-22-21-11-9-20(28)17-19(21)8-10-23(22)24(27)12-13-25(27)30-26(29)14-7-18-5-3-2-4-6-18/h2-6,17,21-25H,7-16H2,1H3
• InChI key: UBWXUGDQUBIEIZ-UHFFFAOYSA-N
• Gene Information: human ... INHBA(3624)

Description

General description

Activins are homodimers or heterodimers of the different subunit isoforms, part of the TGF-? super-family. Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, hematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells. BioVision′s Activin A is produced in a serum-free, chemically de?ned media.

Physical form

Lyophilized from a PBS solution.

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable