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Key Documents

SAB5300513

Sigma-Aldrich

Monoclonal Anti-BECN1 antibody produced in mouse

clone 2A4, ascites fluid

Synonym(s):

ATG6, BECN1, VPS30, beclin1

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100 μL
€420.00

€420.00

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100 μL
€420.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

€420.00

Please contact Customer Service for Availability

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

ascites fluid

antibody product type

primary antibodies

clone

2A4, monoclonal

mol wt

60 kDa

species reactivity

human

technique(s)

direct ELISA: 1:10,000
flow cytometry: 1:200-1:400
immunohistochemistry: 1:200-1:1,000
western blot: 1:500-1:2,000

isotype

IgG1

NCBI accession no.

NM_003766.3

UniProt accession no.

Q14457

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BECN1(8678)

Related Categories

Immunogen

Purified recombinant fragment of human BECN1 expressed in E.coli.
Mouse monoclonal antibody raised against BECN1

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Physical form

Ascitic fluid containing 0.03% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
PM1104185

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Tahereh Kashkoulinejad-Kouhi et al.
Oncology reports, 45(2), 665-679 (2021-01-09)
Cisplatin treatment confers the relative resistance to MCF-7 cells as compared to other breast cancer cell lines. One principal reason is that chemotherapeutic agents induce autophagy in these cells to inhibit apoptosis. Binding immunoglobulin protein (BiP), a master regulator of unfolded
Jia Wang et al.
Molecular medicine reports, 12(3), 4210-4218 (2015-06-18)
The aim of the present study was to determine whether liraglutide (LRG), a long acting glucagon-like peptide 1 analogue, exerted a protective effect on free fatty acid (FFA)‑treated pancreatic β‑cells via activating autophagy. INS‑1 insulinoma pancreatic islet cell lines were

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