SAB4702019

Monoclonal Anti-CD82 purified low endotoxin produced in mouse

• Synonym(s): 4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27
• UNSPSC Code: 12352203

Properties

• conjugate: unconjugated
• Quality Level: 100
• antibody product type: primary antibodies
• clone: C33, monoclonal
• form: buffered aqueous solution
• species reactivity: human
• concentration: 1 mg/ml
• technique(s): FUNC: suitable; flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• isotype: IgG2a
• UniProt accession no.: P27701
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... CD82(3732)

Description

General description

CD82 (KAI1), a member of the tetraspanin family, forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules. These complexes influence adhesion, morphology, activation, proliferation and differentiation of B, T and other cells. CD82 regulates cytoskeleton rearrangement and may participate in the turnover of the tetraspanin complex members. Besides in the plasma membrane, CD82 is localized also in endosome/lysosome compartments. Tumour-suppressive roles of CD82 have been demonstrated.

Specificity

The mouse monoclonal antibody C33 recognizes an extracellular/luminal epitope of CD82, a widely expressed cell surface protein of the tetraspanin family. CD82 is also found in endosome/lysosome compartments.

Immunogen

C91/PL (human HTLV-1+ T cell line)

Physical form

Phosphate buffered saline (PBS), pH 7.4

Preparation Note

Purified by protein-A affinity chromatography.

Storage and Stability

Store at 2-8°C. Do not freeze.

Other Notes

The antibody solution should be gently mixed before use.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1