XIAP associated factor 1 (XAF1) is a cytokine-regulated protein expressed in the cytoplasm. It contains a tumor necrosis factor receptor-associated factor (TRAF) domain. The gene encoding XAF1 is localized on human chromosome 17p13.1.
Immunogen
Synthetic peptide from human XAF1/XIAP-assoicated factor 1
Application
Anti-XAF1 antibody produced in rabbit has been used in Western blotting.
Biochem/physiol Actions
XIAP associated factor 1 (XAF1) is an inhibitor of tumor growth. It has a role in restoring X-linked inhibitor of apoptosis (XIAP)-suppressed caspase activity.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Solution in phosphate-buffered saline containing 0.02% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Here we report an integrated analysis that leverages data from treatment of genetic mouse models of prostate cancer along with clinical data from patients to elucidate new mechanisms of castration resistance. We show that castration counteracts tumor progression in a
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer
Andrea Lunardi
Nature Genetics (2013)
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.