Synthetic peptide directed towards the C terminal region of human PDS5A
Biochem/physiol Actions
PDS5A belongs to the PDS5 family. It contains 1 HEAT repeat and 3 LRR (leucine-rich) repeats. PDS5A may contribute to regulation of sister chromatid cohesion during mitosis.
Sequence
Synthetic peptide located within the following region: PPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEA
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
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Polycomb Repressive Complexes 1 and 2 (PRC1, PRC2) are conserved epigenetic regulators that promote transcriptional gene silencing. PRC1 and PRC2 converge on shared targets, catalyzing repressive histone modifications. Additionally, a subset of PRC1/PRC2 targets engage in long-range interactions whose functions
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