The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. NUP54 is a member of the phe-gly (FG) repeat-containing nucleoporin subset.
Immunogen
NUP54 (NP_059122, 302-336) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human NUP54.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
p63, more specifically its ΔNp63α isoform, plays essential roles in squamous cell carcinomas (SCCs), yet the mechanisms controlling its nuclear transport remain unknown. Nucleoporins (NUPs) are a family of proteins building nuclear pore complexes (NPC) and mediating nuclear transport across
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