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EMU083541

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Lpl

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGGTGGACATCGGAGAACTGCTCATGATGAAGCTTAAGTGGATGAGCGACTCCTACTTCAGCTGGCCCGACTGGTGGAGCAGCCCCAGCTTCGTCATCGAGAGGATCCGAGTGAAAGCCGGAGAGACTCAGAAAAAGGTCATCTTCTGTGCTAGGGAGAAAGTTTCTCATCTGCAGAAGGGAAAGGACTCAGCAGTGTTTGTGAAATGCCATGACAAGTCTCTGAAGAAGTCTGGCTGACACTGGACAAACAAACAAGAGAAGAAAGCATCCGAGTTCTTTGAAGACAGAAGAAAACAAAGTAAATTTAATTTAAAAAAATAATACCCTTGTTTGGGTGTTTGAAAGTGGGTTTTCCTGAGTATTAATCCCAGCTCTATCTTGTTAGTTAAACAGAAGACAGTCTCAAATATTAAACGGTGGCTAACCCAGGGTGAGGAATCTAATGGCCCATAGCAGGTCTTCCAGCATCAGAAGACATCAGGCA

Ensembl | mouse accession no.

ENSMUSG00000015568

NCBI accession no.

NM_008509

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... LPL(16956) , Lpl(16956)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ping-Ping He et al.
Biochimie, 106, 81-90 (2014-08-26)
Accumulating evidence suggests that microRNA-590 (miR-590) has protective effects on cardiovascular diseases, but the mechanism is unknown. Interestingly, previous studies from our laboratory and others have shown that macrophage-derived lipoprotein lipase (LPL) might accelerate atherosclerosis by promoting lipid accumulation and
Majib Jan et al.
Biochemical and biophysical research communications, 462(1), 33-37 (2015-05-02)
In previous studies, we demonstrated that down-regulation of lipoprotein lipase in L6 muscle cells increased insulin-stimulated glucose uptake. In the current study, we used RNA interference technology to silence the LPL gene in L6 cells and generate a LPL-knock-down (LPL-KD)
Uri Rozovski et al.
Molecular cancer research : MCR, 13(5), 944-953 (2015-03-04)
While reviewing chronic lymphocytic leukemia (CLL) bone marrow slides, we identified cytoplasmic lipid vacuoles in CLL cells but not in normal B cells. Because lipoprotein lipase (LPL), which catalyzes hydrolysis of triglycerides into free fatty acids (FFA), is aberrantly expressed

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