P5413

Poly(ethylene glycol)

for molecular biology, average mol wt 8,000

• Synonym(s): Poly (ethylene oxide), Polyethylene glycol, PEG
• Linear Formula: H(OCH₂CH₂)_nOH
• CAS Number: 25322-68-3
• MDL number: MFCD00081839
• UNSPSC Code: 12352104
• PubChem Substance ID: 24898639
• NACRES: NA.31

Properties

• grade: for molecular biology
• Quality Level: 300
• form: powder
• mol wt: average mol wt 8,000
• solubility: water: soluble (approximately 630 mg/ml, 20 °C)
• density: 1.0845 g/mL at 70 °C; 1.0689 g/mL at 90 °C
• foreign activity: DNase, RNase and NICKase, none detected
• SMILES string: C(CO)O
• InChI: 1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
• InChI key: LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

General description

Polyethylene glycol (PEG) is a polymer of ethylene oxide and water, obtained upon condensation.[1] PEGs are susceptible to oxidative degradation in the presence of air. Minimizing the exposure of PEG to elevated temperatures and/or exposure to oxygen or addition of an antioxidant can limit the amount of degradation. PEGs do not hydrolyze or deteriorate upon storage. PEGs do not support the growth of molds.[2]

Polyethylene glycol (PEG) is used in detergents, emulsifying agents, soaps, metal costing process, pharmaceutical preparations and cosmetics.[1] PEG is commonly used as a lubricant. It′s application is also observed in chromatographic stationary phases.[2] PEG prevents crystal formation in emulsions.[3]

Application

Poly(ethylene glycol) has been used:

• in protoplast suspension[4]
• to prevent phase separation in emulsion[3]
• in phage tail-like particles precipitation[5]
• for purifying and intensifying products of polymerase chain reaction[6]

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves