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A156

Supelco

(±)-N-Allylnormetazocine hydrochloride

analytical standard

Synonym(s):

(2α,6α)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol

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About This Item

Empirical Formula (Hill Notation):
C17H23NO · HCl
CAS Number:
7619-35-4
Molecular Weight:
293.83
MDL number:
MFCD00151708
UNSPSC Code:
41116107
PubChem Substance ID:
329770714
NACRES:
NA.24

grade

analytical standard

Quality Level

100

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

Cl.[H]C1(C)C2Cc3ccc(O)cc3C1(C)CCN2CC=C

InChI

1S/C17H23NO.ClH/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17;/h4-6,11-12,16,19H,1,7-10H2,2-3H3;1H

InChI key

ZTGMHFIGNYXMJV-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Vân-Ly Phan et al.
Journal of neuroscience research, 79(4), 561-572 (2005-01-07)
The sigma1 receptor is a unique intracellular receptor whose activation results in an efficient modulation of several neurotransmitter responses. Its role as a target for the rapid nongenomic effects of neuro(active)steroids and the age-related diminutions in steroid levels suggested that
J Kitanaka et al.
Psychopharmacology, 203(4), 781-792 (2008-12-05)
The effects of sigma receptor antagonists on methamphetamine (METH)-induced stereotypy have not been examined. We examined the effects of sigma antagonists on METH-induced stereotypy in mice. The administration of METH (10 mg/kg) to male ddY mice induced stereotyped behavior consisting
José Francisco Navarro et al.
Psicothema, 24(3), 427-430 (2012-07-04)
Recently, sigma-1 receptor modulators have been considered drugs with an interesting therapeutic potential for the treatment of anxiety. However, there is no clear information in preclinical studies about the possible effects of sigma-1 ligands on anxiety in experimental animal models.
Mitsuo Tanabe
Neuropharmacology, 53(3), 406-414 (2007-07-17)
Using whole-cell voltage-clamp recordings, hyperpolarization-activated cation currents (Ih) were elicited with hyperpolarizing voltage jumps in CA1 pyramidal neurons of rat hippocampal slices, and the effects of phencyclidine (PCP) and some sigma ligands on Ih were studied. PCP concentration-dependently (0.1-100 microM)
Nobuaki Egashira et al.
European journal of pharmacology, 563(1-3), 149-154 (2007-03-14)
In the present study, we examined the involvement of the sigma1 receptor in the inhibitory effect of the selective serotonin reuptake inhibitor (SSRI) fluvoxamine, compared with that of paroxetine, on marble-burying behavior, which is an animal model of obsessive-compulsive disorder.
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