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46149

Supelco

Corticosterone 21-acetate

VETRANAL®, analytical standard

Synonym(s):

11β,21-Dihydroxy-4-pregnene-3,20-dione 21-acetate, 4-Pregnene-11β,21-diol-3,20-dione 21-acetate

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About This Item

Empirical Formula (Hill Notation):
C23H32O5
CAS Number:
1173-26-8
Molecular Weight:
388.50
Beilstein:
3225312
EC Number:
214-635-8
MDL number:
MFCD00010482
UNSPSC Code:
41116107
PubChem Substance ID:
329757088
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@]4(C)[C@H](CC[C@@]24[H])C(=O)COC(C)=O

InChI

1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1

InChI key

WKQCPUMQBMFPLC-ZWFCQKKLSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBW2963
SZBD022XV
SZB8016XV
SZE8016X
8016X

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Matthew N Hill et al.
European journal of pharmacology, 528(1-3), 99-102 (2005-12-06)
This research was designed to examine the effect of three weeks of administration of corticosterone (20 mg/kg) on endocannabinoid content and cannabinoid CB1 receptor binding in the amygdala. It was found that the endocannabinoid 2-arachidonylglycerol was significantly increased in the
B L Tepperman et al.
The American journal of physiology, 250(5 Pt 1), G617-G624 (1986-05-01)
Gastric mucosal responses to intraluminal instillation of acid (10, 50, and 150 mM HCl) and acidified solutions of sodium taurocholate (10 mM) were measured in rats between 5 and 60 days after birth. Net loss of H+ and gain of
L E Flores et al.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 120(1), 77-81 (1998-11-25)
The aim of this work was to demonstrate the possible direct effect of several hormones upon glucose-induced insulin secretion in amphibians. Hence, pancreas pieces of Bufo arenarum were incubated for 60 min at 25 degrees with 2 and 8 mM
E G Long et al.
Laboratory investigation; a journal of technical methods and pathology, 54(6), 609-615 (1986-06-01)
Male Sprague-Dawley rats were immunosuppressed by subcutaneous injections of cortisone acetate for 8 weeks to induce Pneumocystis carinii pneumonia. Rats were killed with ether, their lungs were filled in situ with cold glutaraldehyde, and sections were examined by transmission electron
R Chirino et al.
Endocrinology, 129(6), 3118-3124 (1991-12-01)
The low affinity glucocorticoid binding sites (LAGS) have been described and partially characterized in both the nuclei and microsomes of rat liver. The LAGS concentration is under endocrine regulation, as proved by their decrease after adrenalectomy and their almost complete
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