Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

33871

Supelco

2-Nitrobenzaldehyde semicarbazone

VETRANAL®, analytical standard

Synonym(s):

2-NP-SCA, 4-(2-Nitrobenzylidene)semicarbazide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C8H8N4O3
CAS Number:
16004-43-6
Molecular Weight:
208.17
MDL number:
MFCD00160990
UNSPSC Code:
41116107
PubChem Substance ID:
329754682
NACRES:
NA.24

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

NC(=O)N\N=C\c1ccccc1[N+]([O-])=O

InChI

1S/C8H8N4O3/c9-8(13)11-10-5-6-3-1-2-4-7(6)12(14)15/h1-5H,(H3,9,11,13)/b10-5+

InChI key

OEOKLBSECDAYSM-BJMVGYQFSA-N

General description

2-Nitrobenzaldehyde semicarbazone is a semicarbazone derivative of 2-Nitrobenzaldehyde.[1]

Application

2-Nitrobenzaldehyde semicarbazone (2-NBA-SC) may be used as an analytical reference standard for the determination of 2-NBA-SC in:
  • Animal muscle tissues by solid-phase extraction (SPE) and high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) equipped with electrospray ionization (ESI) source and multiple reaction monitoring (MRM) detection.[2]
  • Milk of dairy cows by LC-MS/MS with selected reaction monitoring (SRM) detection.[3]
  • Azodicarbonamide-treated flour samples by isotope dilution liquid chromatography coupled to ESI-LC-MS/MS.[4]
  • Shrimp dosed with nitrofurans by ESI-LC-MS/MS with SRM detection.[5]

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Derivatized standard for the assay of nitrofurans in animal tissue by LC/MS

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBX0564
BCBV4541
BCBT3403

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Microwave-assisted Synthesis and Bioevaluation of Some Semicarbazones.
Jafri L, et al.
Chemical Biology & Drug Design, 79(6), 950-959 (2012)
Liquid chromatography- tandem mass spectrometry for the determination of protein-bound residues in shrimp dosed with nitrofurans.
Chu PS and Lopez MI
Journal of Agricultural and Food Chemistry, 53(23), 8934-8939 (2005)
Determination of the metabolites of nitrofuran antibiotics in animal tissue by high-performance liquid chromatography-tandem mass spectrometry.
Leitner A, et al.
Journal of Chromatography A, 939(1-2), 49-58 (2001)
Determination of nitrofuran residues in milk of dairy cows using liquid chromatography- tandem mass spectrometry.
Chu PS and Lopez MI
Journal of Agricultural and Food Chemistry, 55(6), 2129-2135 (2007)
Adam Becalski et al.
Journal of agricultural and food chemistry, 52(18), 5730-5734 (2004-09-18)
Semicarbazide was previously found in foods that were in contact with rubber gaskets foamed at high temperatures with a blowing agent azodicarbonamide. Because azodicarbonamide is an approved flour additive in certain countries, we set out to ascertain if semicarbazide is

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service