16254

Thymol

meets analytical specification of Ph. Eur., BP, NF, 99-101%

• Synonym(s): 2-Isopropyl-5-methylphenol, 5-Methyl-2-(1-methylethyl)phenol, 5-Methyl-2-isopropylphenol, IPMP
• Linear Formula: 2-[(CH₃)₂CH]C₆H₃-5-(CH₃)OH
• CAS Number: 89-83-8
• Molecular Weight: 150.22
• Beilstein: 1907135
• EC Number: 201-944-8
• MDL number: MFCD00002309
• UNSPSC Code: 12171500
• eCl@ss: 39023311
• PubChem Substance ID: 57647553
• NACRES: NA.47

Properties

• vapor pressure: 1 mmHg ( 64 °C)
• Quality Level: 200
• Assay: 99-101%
• form: solid
• quality: meets analytical specification of Ph. Eur., BP, NF
• impurities: acidic reac. impurities, complies; organic volatile impurities, complies (GC); related subst., complies (GC); residual solvents, complies; ≤0.05% non-volatile matter
• bp: 232 °C (lit.)
• mp: 48-51 °C (lit.); 48-51 °C
• density: 0.965 g/mL at 25 °C (lit.)
• suitability: complies for appearance of solution
• SMILES string: CC(C)c1ccc(C)cc1O
• InChI: 1S/C10H14O/c1-7(2)9-5-4-8(3)6-10(9)11/h4-7,11H,1-3H3
• InChI key: MGSRCZKZVOBKFT-UHFFFAOYSA-N

Description

Application

Thymol has been used to study:

• the effect of thymol on the viability of Bacillus cereus.[1]
• its effect on growth and production of citrinin from Penicillium citrinum.[2]
• the effect of thymol on insect and human γ-aminobutyric acid (GABA) receptors.[3]

Biochem/physiol Actions

Thymol (5-methyl-2-isopropylphenol), a monocyclic phenolic compound, is a vital constituent of Thymus vulgaris essential oil. It has been used in dental preparations to kill odor-producing bacteria. Thymol serves as a preservative through its antimicrobial and antioxidant properties. In addition, thymol also has molluscicidal and insecticidal properties. Thymol acts as an allosteric modulator of human γ-aminobutyric acid (GABA_A) receptors.[3]

Disclaimer

The product is not intendedfor use as a biocide under global biocide regulations, including but notlimited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, EuropeanBiocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’sBiocidal Products Regulation, Korea’s Consumer Chemical Products and BiocideSafety Management Act (K-BPR) and others.

Safety Information

• Pictograms: GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302,H314,H411
• Precautionary Statements: P260 - P273 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 2
• Flash Point(F): 240.8 °F - closed cup
• Flash Point(C): 116 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves