Journal of biochemistry, 125(2), 383-390 (1999-02-17)
We have investigated the effect of phenolic antioxidants on cisplatin-induced cytotoxicity in vero (African Green Monkey Kidney) cells and in rat renal cortical slices in vitro, and on cisplatin-induced nephrotoxicity in rats in vivo. Incubation of cisplatin with vero cells
Inhibition of albumin denaturation and antiinflammatory activity of dehydrozingerone and its analogs.
G Elias et al.
Indian journal of experimental biology, 26(7), 540-542 (1988-07-01)
Journal of cardiovascular pharmacology, 52(5), 422-429 (2008-11-27)
Growth factor and oxidative stress-mediated migration and proliferation of vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of atherosclerosis. The objective of this study was to assess the ability of dehydrozingerone, a structural analog of curcumin
The antioxidant property of dehydrozingerone and its analogs were investigated in the ferric-ascorbate induced lipid peroxidation model in rat brain homogenate. All the non phenolic compounds were either inactive or less active, while phenolic compounds with substitution at both meta
The antioxidant properties of three related compounds, dehydrozingerone, isoeugenol and eugenol, were investigated using various models. Isoeugenol was found to be the most active in inhibiting ferrous-ion-, ferric-ion- and cumene-hydroperoxide-induced lipid peroxidation in rat brain homogenates. These compounds also showed
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