02390
1,2-Ethanedithiol
≥98.0% (GC)
Synonym(s):
1,2-Dimercaptoethane, Dithioglycol, Ethylene mercaptan
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25 ML
€40.70
100 ML
€104.00
500 ML
€295.00
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25 ML
€40.70
100 ML
€104.00
500 ML
€295.00
About This Item
Linear Formula:
HSCH2CH2SH
CAS Number:
Molecular Weight:
94.20
Beilstein:
505946
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form:
liquid
Assay:
≥98.0% (GC)
Recommended Products
vapor density
>1 (vs air)
Quality Level
vapor pressure
4.8 mmHg ( 20 °C)
Assay
≥98.0% (GC)
form
liquid
refractive index
n20/D 1.558 (lit.)
n20/D 1.558
bp
144-146 °C (lit.)
mp
−41 °C (lit.)
density
1.123 g/mL at 25 °C (lit.)
functional group
thiol
SMILES string
SCCS
InChI
1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2
InChI key
VYMPLPIFKRHAAC-UHFFFAOYSA-N
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General description
1,2-Ethanedithiol (EDT) is an organosulfur compound that is used as an organic building block in chemical synthesis. It is also used as a ligand for metal ions to prepare metal complexes.
Application
1,2-Ethanedithiol can be used to synthesize:
- 1,3-Dithiolanes by reacting with aldehydes or ketones.
- Dithiazepan-3-yl-alkanoic acids by cyclocondensation reaction with amino acids and formaldehyde.
- EDT can also be used as a scavenger in solid phase peptide synthesis for the efficient deprotection of the peptide resin.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 3
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
111.2 °F - closed cup
Flash Point(C)
44 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Reaction conditions were defined for the selective quantitative derivatization and fluorophore labeling of phosphoserine residues on peptides and proteins. Phosphoserine was derivatized with 1,2-ethanedithiol using a modification of the reaction conditions defined by R. C. Clark and J. Dijkstra (1967)
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The heat resistance of wild-type spores of Bacillus subtilis or spores (termed alpha-beta-) lacking DNA protective alpha/beta-type small, acid-soluble spore proteins was not altered by anaerobiosis or high concentrations of the free radical scavenging agents ethanethiol and ethanedithiol. Heat-killed wild-type
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Pseudomonas aeruginosa and Burkholderia cenocepacia (formally, genomovar III genotype of Burkholderia cepacia complex) have emerged as serious opportunistic resistant pathogens in patients with cystic fibrosis (CF). We have developed a liposomal formulation containing bismuth-ethanedithiol (BiEDT) and tobramycin to overcome bacterial
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