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AB9842

Sigma-Aldrich

Anti-phospho-Munc-18 (Ser515) Antibody

Chemicon®, from rabbit

Synonym(s):

ANC18HA, Munc18-1, n-Sec1, nSsec1, NSEC1A, p67, Protein unc-18 homolog 1, Protein unc-18 homolog A, rbSec1, rbSec1A, rbSec1B, Sec1, Syntaxin-binding protein 1, Unc18-1, Unc-18A, Unc-18 homolog, Stxbp1, Unc18a

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_013038.3

UniProt accession no.

P61765

shipped in

dry ice

target post-translational modification

phosphorylation (pSer515)

Gene Information

rat ... Stxbp1(25558)

Specificity

Munc-18, phospho Serine 515. The antibody recognizes a protein of ~65 kDa corresponding to Munc-18, phospho Serine 515 in lysates from rat cortex. Immunolabeling is blocked by the phosphopeptide used as the immunogen but not the corresponding non-phosphopeptide.
The immunogen has 100% homology with human, mouse, non-human primates, bovine, canine, chicken and Xenopus.

Immunogen

Synthetic peptide corresponds to sequence surrounding the phosphoserine 515 site of rat Munc-18.

Application

This Anti-phospho-Munc-18 (Ser515) Antibody is validated for use in WB for the detection of phospho-Munc-18 (Ser515).

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Certificates of Analysis (COA)

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Shatrunjai Giri et al.
Journal of neuroscience research, 99(7), 1815-1834 (2021-04-06)
Rapid eye movement sleep (REMS) favors brain development and memory, while it is decreased in neurodegenerative diseases. REMS deprivation (REMSD) affects several physiological processes including memory consolidation; however, its detailed mechanism(s) of action was unknown. REMS reduces, while REMSD elevates

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