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04-047

Sigma-Aldrich

Anti-CUGBP2 Antibody, clone 1H2

clone 1H2, Upstate®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1H2, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... CELF2(10659)

Specificity

CuGBP2

Immunogen

A synthetic peptide corresponding to amino acids 209-415 of human CuGBP2.

Application

Research Category
Protein Trafficking
Research Sub Category
RNA Metabolism & Binding Proteins

RNA Binding Protein (RBP)
This Anti-CUGBP2 Antibody, clone 1H2 is validated for use in WB for the detection of CUGBP2.

Quality

Routinely evaluated by immunoblot.

Target description

56 kDa

Physical form

100 μg of Protein A purified mouse monoclonal IgG1 in 100μl of 1X PBS, pH 7.0, 0.1% Azide.
Format: Purified
Protein A purified

Storage and Stability

2 years at -20°C from date of shipment

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Debnath Mukhopadhyay et al.
Annals of the New York Academy of Sciences, 1010, 504-509 (2004-03-23)
Posttranscriptional control of gene expression plays a key role in regulating gene expression in cells undergoing apoptosis. Cyclooxygenase-2 (COX-2) is a crucial enzyme in the conversion of arachidonic acid to prostaglandin E2 (PGE(2)) and is significantly upregulated in many types
Cindy Meyer et al.
Molecular cell, 69(4), 622-635 (2018-02-13)
TIA1 and TIAL1 encode a family of U-rich element mRNA-binding proteins ubiquitously expressed and conserved in metazoans. Using PAR-CLIP, we determined that both proteins bind target sites with identical specificity in 3' UTRs and introns proximal to 5' as well as
Gopal Singh et al.
Nucleic acids research, 32(3), 1232-1241 (2004-02-20)
Members of the CUG-BP and ETR-3 like factor (CELF) protein family bind within conserved intronic elements (called MSEs) flanking the cardiac troponin T (cTNT) alternative exon 5 and promote exon inclusion in vivo and in vitro. Here we use a
P Lichtner et al.
Journal of molecular medicine (Berlin, Germany), 80(7), 431-442 (2002-07-12)
Partial monosomy 10p is a rare chromosomal aberration. Patients often show symptoms of the DiGeorge/velocardiofacial syndrome spectrum. The phenotype is the result of haploinsufficiency of at least two regions on 10p, the HDR1 region associated with hypoparathyroidism, sensorineural deafness, and

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