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878124C

Avanti

C16-22:6 PC

Avanti Research™ - A Croda Brand 878124C

Synonym(s):

1-O-hexadecyl-2-docosahexaenoyl-sn-glycero-3-phosphocholine

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About This Item

Empirical Formula (Hill Notation):
C46H82NO7P
CAS Number:
132213-85-5
Molecular Weight:
792.12
UNSPSC Code:
12352211
NACRES:
NA.25

form

liquid

packaging

pkg of 1 × 1 mL (878124C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 878124C

concentration

5 mg/mL (878124C-5mg)

lipid type

phosphoglycerides
bioactive lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COCCCCCCCCCCCCCCCC)=O

InChI

1S/C46H82NO7P/c1-6-8-10-12-14-16-18-20-22-23-24-25-26-27-29-31-33-35-37-39-46(48)54-45(44-53-55(49,50)52-42-40-47(3,4)5)43-51-41-38-36-34-32-30-28-21-19-17-15-13-11-9-7-2/h8,10,14,16,20,22,24-25,27,29,33,35,45H,6-7,9,11-13,15,17-19,21,23,26,28,30-32,34,36-44H2,1-5H3/b10-8-,16-14-,22-20-,25-24-,29-27-,35-33-/t45-/m1/s1

InChI key

QQQQNYAHSSIZBU-HIQXTUQZSA-N

General description

Phophotidylcholine (PC) is a glycerophospholipid. It is synthesized in by the CDP-choline pathway or Kennedy pathway. PC is present at higher concentrations in all mammalian cells and organelles.

Application

C16-22:6 PC has been used as a lipid reference standard in matrix assisted laser desorption/ionization- time-of-light (MALDI-TOF) mass spectrometry.

Biochem/physiol Actions

Phophotidylcholine (PC) plays a role in cellular and human physiology. It is a housekeeping component that is involved in maintaining the integrity of cell membranes. PC is an essential component for the synthesis of very low density lipoprotein (VLDL) from hepatocytes. It is also implicated in myelinating the nerve cells.

Packaging

5 mL Clear Glass Sealed Ampule (878124C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Characteristic oxidation products of choline plasmalogens are detectable in cattle and roe deer spermatozoa by MALDI-TOF mass spectrometry
Fuchs B, et al.
Lipids, 42(11), 991-998 (2007)
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease
van der Veen J N, et al.
Biochimica et Biophysica Acta - Biomembranes (2017)
From yeast to humans-roles of the Kennedy pathway for phosphatidylcholine synthesis
McMaster C R
Febs Letters, 592(8), 1256-1272 (2018)
A review on phospholipids and their main applications in drug delivery systems
Li J, et al.
Asian Journal of Pharmaceutical Sciences , 10(2), 81-98 (2015)

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