857459P

16:1 aldehyde

Avanti Research^™ - A Croda Brand 857459P, powder

• Synonym(s): (2E)-hexadecenal
• Empirical Formula (Hill Notation): C₁₆H₃₀O
• CAS Number: 3163-37-9
• Molecular Weight: 238.41
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 1 mg (857459P-1mg); pkg of 1 × 5 mg (857459P-5mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 857459P
• lipid type: sphingolipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: CCCCCCCCCCCCC/C=C/C([H])=O
• InChI: 1S/C16H30O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h14-16H,2-13H2,1H3/b15-14+
• InChI key: KLJFYXOVGVXZKT-CCEZHUSRSA-N

Description

General description

Fatty aldehydes are enzymatically converted to fatty alcohols and fatty acids. When assessing S1P lyase enzymatic activity, the estimation of fatty aldehyde stability during the reaction is required. The (2E)-hexadecenal(d5) (857461) is suitable as the internal standard for LC/MS/MS approaches to quantify the product of S1P degradation by S1P lyase, (2E)-hexadecenal; however, a natural (2E)-hexadecenal (857469) is needed to evaluate its stability during enzymatic reaction. The method describing the details of the use of both (2E)-hexadecenal(d5) and (2E)-hexadecenal for LC/MS/MS-based characterization of S1P lyase reaction is in preparation for publication by Berdyshev et al.Personal communication from Evgeny Berdyshev, Ph.D., Assistant Professor, University of Illinois at Chicago.

Application

16:1 aldehyde ((2E)-hexadecenal) has been used as an internal standard for extraction and detection of derivatized fatty aldehydes from HepG2 cell line by high performance liquid chromatography-electrospray ionization-quadrupole/time-of flight mass spectrometry (HPLC-ESI-QTOF).

Biochem/physiol Actions

16:1 aldehyde is a predominant fatty aldehyde in phospholipid of bacteria like Selenomonas ruminantium, when grown on glucose and even-numbered volatile fatty acids, and lactobacillus. It is one of the main aldehydes in phosphatidylethanolamine plasmalogen of Ophiura sarsi and choline and ethanolamine phospholipid component of bovine adipose tissue.

Packaging

5 mL Amber Glass Screw Cap Vial (857459P-1mg)

5 mL Amber Glass Screw Cap Vial (857459P-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3