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W379301

Sigma-Aldrich

D-(−)-Ribose

≥98%

Synonym(s):

Dextro-ribose

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About This Item

Empirical Formula (Hill Notation):
C5H10O5
CAS Number:
50-69-1
Molecular Weight:
150.13
FEMA Number:
3793
Beilstein:
1723081
EC Number:
200-059-4
MDL number:
MFCD00135453
UNSPSC Code:
12352201
PubChem Substance ID:
24901881
NACRES:
NA.21

biological source

synthetic

reg. compliance

FDA 21 CFR 117

Assay

≥98%

optical activity

[α]21/D −19.7°, c = 4 in H2O

mp

88-92 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

odorless

SMILES string

OC[C@@H](O)[C@@H](O)[C@@H](O)C([H])=O

InChI

1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1

InChI key

PYMYPHUHKUWMLA-LMVFSUKVSA-N

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General description

D-(−)-Ribose has been in an in vitro study of the effect of non-enzymatic ribation in modifying bone collagen leading to bone fragility.

Application

  • Protective effect of thymoquinone on glycation of human myoglobin induced by d-ribose.: This study investigates the protective effects of thymoquinone against d-ribose-induced glycation in human myoglobin, highlighting potential therapeutic applications in preventing protein glycation (Liu et al., 2023).

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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D-ribose and deoxy-D-ribose induce apoptosis in human quiescent peripheral blood mononuclear cells.
Barbieri D, et al.
Biochemical and Biophysical Research Communications, 201(3), 1109-1116 (1994)
Alice Pavlowsky et al.
Current biology : CB, 28(11), 1783-1793 (2018-05-22)
Memory consolidation is a crucial step for long-term memory (LTM) storage. However, we still lack a clear picture of how memory consolidation is regulated at the neuronal circuit level. Here, we took advantage of the well-described anatomy of the Drosophila
Anders Virtanen et al.
Critical reviews in biochemistry and molecular biology, 48(2), 192-209 (2013-03-19)
Deadenylation of eukaryotic mRNA is a mechanism critical for mRNA function by influencing mRNA turnover and efficiency of protein synthesis. Here, we review poly(A)-specific ribonuclease (PARN), which is one of the biochemically best characterized deadenylases. PARN is unique among the
Carine Baraguey et al.
Organic & biomolecular chemistry, 11(16), 2638-2647 (2013-03-05)
The pivaloyloxymethyl (PivOM) group is a biolabile 2'-O-ribose protection that is under development in a prodrug-based approach for siRNA applications. Besides an expected cellular uptake, nucleic acid sequences carrying PivOM showed also increased nuclease resistance and, in most cases, an
Xiang-Guo Li et al.
Chemical communications (Cambridge, England), 49(35), 3682-3684 (2013-03-29)
Peptide glycosylation with 5-deoxy-5-[(18)F]fluororibose was translated into preclinical settings. The novel (18)F-labeled Siglec-9 peptide was produced using an automated synthesis procedure. The (18)F-labeled Siglec-9 peptide showed favorable binding in the animal model of inflammation in vivo.
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