The 4-alkylamino-5-nitroquinolines (5NQs) are a new series of bioreductive drugs that exhibit varying degrees of selective toxicity (up to 60-fold) under hypoxic conditions in cell culture. This study tested the hypothesis that differences in hypoxia-selective cytotoxicity in this series reflect
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 79(3), 412-417 (2011-04-20)
Photophysical properties of 5-aminoquinoline (5AQ) have been investigated in various non-polar and polar (protic and aprotic) solvents using steady state and time resolved fluorescence. In aprotic solvents, the spectral maxima depend on the polarity. However, in protic solvents both the
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 74(5), 1215-1223 (2009-10-27)
The Fourier transform infrared (FTIR) and FT-Raman spectra of 5-aminoquinoline (5AQ) have been recorded in the range 4000-400 and 3500-100 cm(-1), respectively. The complete vibrational assignment and analysis of the fundamental modes of the compounds were carried out using the
Indian journal of biochemistry & biophysics, 30(4), 229-233 (1993-08-01)
In vitro oxidation and acetylation of 5-aminoquinoline by rabbit liver enzyme preparation has been investigated. Incubation of 5-aminoquinoline with cytosol fraction of the enzyme preparation in the presence of acetyl coenzyme-A gave rise to three different products, viz. 5-amino-2-hydroxy quinoline
Analytical and bioanalytical chemistry, 411(6), 1169-1180 (2019-01-09)
Atmospheric solids analysis probe mass spectrometry (ASAP-MS) was used for the first time for direct surface analysis of plant material. It can be readily used for surface analysis of whole and intact pea seeds and their seed coats, and for
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